CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027964
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Prolyl 4-hydroxylase alpha-related protein PH4[alpha]EFB 
Protein Synonyms/Alias
 Prolyl-4-hydroxylase-alpha EFB; SD05564p 
Gene Name
 PH4alphaEFB 
Gene Synonyms/Alias
 PH4-alpha-EFB; CG31022; Dmel_CG31022 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
526GTKWVSNKWIHERGQacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 550 AA 
Protein Sequence
MAADWRLMLL LGILLLVGGP ANGEVYTALA EMEELLETES VLITNLEGYI RVQEDKLNFL 60
KNKMDEYQRE HSDASHDITA YVSNPINAYL LTKRLTTDWR QVENLMEHDV GTDFLQNITQ 120
YRSLLKFPSD EDLNGAAVAL LRLQDTYQLD TSSVARGKLN GIQYSTEMSS DDCFELGRQS 180
YVNHDYYHTV LWMNEAMARM LEEPTNHTQS FTKADILEYL AFSTYKEGNI ESALTMTNEL 240
LQLLPHHERA NGNKRFYEKE IAQQLQLRKM KGDDGTDEMP KSDLPVAKSD PAIFDMTERR 300
AYEMLCRGEL KPSPSDLRSL RCRYVTNRVP FLRLGPLKLE EVHADPYIVI YHDAMYDSEI 360
DLIKRMARPR FRRATVQNSV TGALETANYR ISKSAWLKTQ EDRVIETVVQ RTADMTGLDM 420
DSAEELQVVN YGIGGHYEPH FDFARKEEQR AFEGLNLGNR IATVLFYMSD VEQGGATVFT 480
SLHTALFPKK GTAAFWMNLH RDGQGDVRTR HAACPVLTGT KWVSNKWIHE RGQEFRRPCD 540
LEEDHGEFAI 550 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
 GO:0004656; F:procollagen-proline 4-dioxygenase activity; IEA:EC. 
Interpro
 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph.
 IPR013547; Pro_4_hyd_alph_N.
 IPR011990; TPR-like_helical. 
Pfam
 PF03171; 2OG-FeII_Oxy
 PF08336; P4Ha_N 
SMART
 SM00702; P4Hc 
PROSITE
 PS51471; FE2OG_OXY 
PRINTS