| Tag | Content |
|---|
| CPLM ID | CPLM-006111 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Spindle pole body component 110 |
Protein Synonyms/Alias | Extragenic suppressor of CMD1-1 mutant protein 1; Nuclear filament-related protein 1; Spindle pole body spacer protein SPC110 |
Gene Name | SPC110 |
Gene Synonyms/Alias | NUF1; XCM1; YDR356W; D9476.3 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 331 | QNESKRLKDELNELE | acetylation | [1] |
|
Reference | [1] mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases. Mitchell L, Huard S, Cotrut M, Pourhanifeh-Lemeri R, Steunou AL, Hamza A, Lambert JP, Zhou H, Ning Z, Basu A, Côté J, Figeys DA, Baetz K. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1641-50. [ PMID: 23572591] |
Functional Description | Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth. |
Sequence Annotation | REGION 900 927 Calmodulin-binding.
MOTIF 54 59 Nuclear localization signal (Potential).
MOTIF 726 731 Nuclear localization signal (Potential).
MOTIF 742 747 Nuclear localization signal (Potential).
MOD_RES 18 18 Phosphothreonine.
MOD_RES 60 60 Phosphoserine; by MPS1.
MOD_RES 64 64 Phosphothreonine; by MPS1.
MOD_RES 68 68 Phosphothreonine; by MPS1.
MOD_RES 80 80 Phosphoserine.
MOD_RES 529 529 Phosphoserine. |
Keyword | 3D-structure; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 944 AA |
Protein Sequence | MDEASHLPNG SLKNMEFTPV GFIKSKRNTT QTQVVSPTKV PNANNGDENE GPVKKRQRRS 60
IDDTIDSTRL FSEASQFDDS FPEIKANIPP SPRSGNVDKS RKRNLIDDLK KDVPMSQPLK 120
EQEVREHQMK KERFDRALES KLLGKRHITY ANSDISNKEL YINEIKSLKH EIKELRKEKN 180
DTLNNYDTLE EETDDLKNRL QALEKELDAK NKIVNSRKVD DHSGCIEERE QMERKLAELE 240
RKLKTVKDQV LELENNSDVQ SLKLRSKEDE LKNLMNELNE LKSNAEEKDT QLEFKKNELR 300
KRTNELNELK IKSDEMDLQL KQKQNESKRL KDELNELETK FSENGSQSSA KENELKMLKN 360
KIAELEEEIS TKNSQLIAKE GKLASLMAQL TQLESKLNQR DSQLGSREEE LKKTNDKLQK 420
DIRIAREETV SKDERIIDLQ KKVKQLENDL FVIKKTHSES KTITDNELES KDKLIKILEN 480
DLKVAQEKYS KMEKELKERE FNYKISESKL EDEKTTLNEK ISNLAAENSQ LKNKIEDNST 540
ATHHMKENYE KQLESLRKDI EEYKESAKDS EDKIEELKIR IAENSAKVSE KRSKDIKQKD 600
EQISDLTQNL KLQEDEISSL KSIIDRYKKD FNQLKSEQSN IQHDLNLQIL NLENKLIESE 660
DELKSLRDSQ KIEIENWKRK YNNLSLENDR LLTEKESASD KEREISILNR KLDEMDKEKW 720
NLQESKEKYK RELQKVITAN DRLRREKEEL NENSNNIRIM EDKMTRIKKN YLSEITSLQE 780
ENRRLEERLI LNERRKDNDS TMQLNDIISY YKLKYHSEVR HNNDLKVIND YLNKVLALGT 840
RRLRLDTRKG EHSLNISLPD DDELDRDYYN SHVYTRYHDY EYPLRFNLNR RGPYFERRLS 900
FKTVALLVLA CVRMKRIAFY RRSDDNRLRI LRDRIESSSG RISW 944 |
Gene Ontology | GO:0005823; C:central plaque of spindle pole body; IDA:SGD. GO:0005822; C:inner plaque of spindle pole body; IDA:SGD. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005200; F:structural constituent of cytoskeleton; IPI:SGD. GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IMP:SGD. GO:0007020; P:microtubule nucleation; IPI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |