| Tag | Content |
|---|
| CPLM ID | CPLM-010177 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc transporter ZitB |
Protein Synonyms/Alias | |
Gene Name | zitB |
Gene Synonyms/Alias | ybgR; b0752; JW0735 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 226 | SLDIAELKRRMCREI | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc, whereas ZntA is required for growth at more toxic concentrations. |
Sequence Annotation | |
Keyword | Cell inner membrane; Cell membrane; Complete proteome; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 313 AA |
Protein Sequence | MAHSHSHTSS HLPEDNNARR LLYAFGVTAG FMLVEVVGGF LSGSLALLAD AGHMLTDTAA 60
LLFALLAVQF SRRPPTIRHT FGWLRLTTLA AFVNAIALVV ITILIVWEAI ERFRTPRPVE 120
GGMMMAIAVA GLLANILSFW LLHHGSEEKN LNVRAAALHV LGDLLGSVGA IIAALIIIWT 180
GWTPADPILS ILVSLLVLRS AWRLLKDSVN ELLEGAPVSL DIAELKRRMC REIPEVRNVH 240
HVHVWMVGEK PVMTLHVQVI PPHDHDALLD QIQHYLMDHY QIEHATIQME YQPCHGPDCH 300
LNEGVSGHSH HHH 313 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005385; F:zinc ion transmembrane transporter activity; IEA:InterPro. GO:0071577; P:zinc ion transmembrane transport; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |