UniProt Accession

 NTF2_RAT; P61972; P13662 

Genbank Protein ID

 X91651; BC061569 

Genbank Nucleotide ID

 CAA62839.1; AAH61569.1 

Protein Name

 Nuclear transport factor 2 

Protein Synonyms/Alias

 NTF-2 

Gene Name

 Nutf2 

Gene Synonyms/Alias

 Ntf2 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
55	GKAAIVEKLSSLPFQ	acetylation	[1]
55	GKAAIVEKLSSLPFQ	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity). 

Sequence Annotation

 DOMAIN 10 121 NTF2.
 MOD_RES 4 4 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 127 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0015630; C:microtubule cytoskeleton; IEA:Compara.
 GO:0006611; P:protein export from nucleus; IEA:Compara. 

Interpro

 IPR002075; NTF2.
 IPR018222; Nuclear_transport_factor_2_euk. 

Pfam

 PF02136; NTF2 

SMART

  

PROSITE

 PS50177; NTF2_DOMAIN 

PRINTS