CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021437
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Threonine aspartase 1 
Protein Synonyms/Alias
 Taspase-1; Threonine aspartase subunit alpha; Threonine aspartase subunit beta 
Gene Name
 TASP1 
Gene Synonyms/Alias
 C20orf13 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39TKQSYKEKRGGFVLVacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Protease involved in KMT2A/MLL1 processing and, consequently, in the correct expression of the early HOXA gene cluster. 
Sequence Annotation
 ACT_SITE 234 234 Nucleophile.  
Keyword
 3D-structure; Autocatalytic cleavage; Complete proteome; Direct protein sequencing; Hydrolase; Protease; Reference proteome; Threonine protease; Zymogen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 420 AA 
Protein Sequence
MTMEKGMSSG EGLPSRSSQV SAGKITAKEL ETKQSYKEKR GGFVLVHAGA GYHSESKAKE 60
YKHVCKRACQ KAIEKLQAGA LATDAVTAAL VELEDSPFTN AGMGSNLNLL GEIECDASIM 120
DGKSLNFGAV GALSGIKNPV SVANRLLCEG QKGKLSAGRI PPCFLVGEGA YRWAVDHGIP 180
SCPPNIMTTR FSLAAFKRNK RKLELAERVD TDFMQLKKRR QSSEKENDSG TLDTVGAVVV 240
DHEGNVAAAV SSGGLALKHP GRVGQAALYG CGCWAENTGA HNPYSTAVST SGCGEHLVRT 300
ILARECSHAL QAEDAHQALL ETMQNKFISS PFLASEDGVL GGVIVLRSCR CSAEPDSSQN 360
KQTLLVEFLW SHTTESMCVG YMSAQDGKAK THISRLPPGA VAGQSVAIEG GVCRLESPVN 420 
Gene Ontology
 GO:0004298; F:threonine-type endopeptidase activity; IMP:UniProtKB.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR000246; Peptidase_T2. 
Pfam
 PF01112; Asparaginase_2 
SMART
  
PROSITE
  
PRINTS