| Tag | Content |
|---|
| CPLM ID | CPLM-031124 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | cDNA FLJ50617, highly similar to Tubulin beta-7 chain |
Protein Synonyms/Alias | |
Gene Name | |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 225 | TQQVFDAKNMMAACD | ubiquitination | [1] | | 290 | DIPPRGLKMAVTFIG | ubiquitination | [1] | | 307 | TAIQELFKRISEQFT | ubiquitination | [1] |
|
Reference | [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA. Mol Cell Proteomics. 2012 May;11(5):148-59. [ PMID: 22505724] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). |
Sequence Annotation | |
Keyword | GTP-binding; Microtubule; Nucleotide-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 372 AA |
Protein Sequence | MDSVRSGPFG QIFRPDNFVF GQSGAGNNWA KGHYTEGAEL VDPVLDVVRK EAESCDCLQG 60
FQLTHSLGGG TGSGMGTLLI SKIREEYPDR IMNTFSVVPS PKVSDTVVEP YNATLSVHQL 120
VENTDETYCI DNEALYDICF RTLKLTTPTY GDLNHLVSAT MSGVTTCLRF PGQLNADLRK 180
LAVNMVPFPR LHFFMPGFAP LTSRGSQQYR ALTVPELTQQ VFDAKNMMAA CDPRHGRYLT 240
AAAVFRGRMS MKEVDEQMLN VQNKNSSYFV EWIPNNVKTA VCDIPPRGLK MAVTFIGNST 300
AIQELFKRIS EQFTAMFRRK AFLHWYTGEG MDEMEFTEAE SNMNDLVSEY QQYQDATAEE 360
EEDFGEEAEE EA 372 |
Gene Ontology | GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |