CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006622
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosome biogenesis protein RPF2 
Protein Synonyms/Alias
  
Gene Name
 RPF2 
Gene Synonyms/Alias
 YKR081C; YKR401 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
271ELDIMGDKLGRIHMGacetylation[1]
284MGKQDLGKLQTRKMKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Required for biogenesis of the 60S ribosomal subunit. 
Sequence Annotation
 DOMAIN 28 243 Brix.
 MOD_RES 73 73 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 344 AA 
Protein Sequence
MIRTVKPKNA RAKRALVKRE AKLVENVKQA LFIPGQSCNK NLHDIMVDLS ALKKPDMKRF 60
NRKNDIHPFE DMSPLEFFSE KNDCSLMVLM TSSKKRKNNM TFIRTFGYKI YDMIELMVAD 120
NFKLLSDFKK LTFTVGLKPM FTFQGAAFDT HPVYKQIKSL FLDFFRGEST DLQDVAGLQH 180
VISMTIQGDF QDGEPLPNVL FRVYKLKSYK SDQGGKRLPR IELVEIGPRL DFKIGRIHTP 240
SPDMVTEAHK KPKQLEMKTK KNVELDIMGD KLGRIHMGKQ DLGKLQTRKM KGLKSKFDQG 300
TEEGDGEVDE DYEDEASYSD DGQEYEEEFV SATDIEPSAK RQKK 344 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0008097; F:5S rRNA binding; IPI:SGD.
 GO:0008312; F:7S RNA binding; IPI:SGD.
 GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. 
Interpro
 IPR007109; Brix. 
Pfam
 PF04427; Brix 
SMART
 SM00879; Brix 
PROSITE
 PS50833; BRIX 
PRINTS