UniProt Accession

 COPZ2_MOUSE; Q9JHH9; A2A6D6 

Genbank Protein ID

 AB047850; AB040137; AF237687; AL596384; BC025122 

Genbank Nucleotide ID

 BAB17661.1; BAA92831.1; AAF37723.1; CAM21891.1; AAH25122.1 

Protein Name

 Coatomer subunit zeta-2 

Protein Synonyms/Alias

 Zeta-2-coat protein; Zeta-2 COP 

Gene Name

 Copz2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
57	DGRRLLAKYYDDTFP	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 205 AA 

Protein Sequence

Gene Ontology

 GO:0030137; C:COPI-coated vesicle; ISS:MGI.
 GO:0030663; C:COPI-coated vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR022775; AP_mu_sigma_su.
 IPR011012; Longin-like_dom. 

Pfam

 PF01217; Clat_adaptor_s 

SMART

  

PROSITE

 PS00989; CLAT_ADAPTOR_S 

PRINTS