Tag | Content |
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CPLM ID | CPLM-009828 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Casein kinase II subunit beta |
Protein Synonyms/Alias | CK II beta; Phosvitin |
Gene Name | Csnk2b |
Gene Synonyms/Alias | Ck2n |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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191 | VPRLYGFKIHPMAYQ | ubiquitination | [1] | 208 | LQAASNFKSPVKTIR | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). Participates in Wnt signaling. |
Sequence Annotation | REGION 188 193 Interaction with alpha subunit (By METAL 109 109 Zinc (By similarity). METAL 114 114 Zinc (By similarity). METAL 137 137 Zinc (By similarity). METAL 140 140 Zinc (By similarity). MOD_RES 2 2 N-acetylserine (By similarity). MOD_RES 2 2 Phosphoserine; by autocatalysis MOD_RES 3 3 Phosphoserine; by autocatalysis (By MOD_RES 209 209 Phosphoserine (By similarity). MOD_RES 212 212 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Wnt signaling pathway; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 215 AA |
Protein Sequence | MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE 60 ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML 120 PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA 180 NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR 215 |
Gene Ontology | GO:0005956; C:protein kinase CK2 complex; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0019887; F:protein kinase regulator activity; IEA:InterPro. GO:0045859; P:regulation of protein kinase activity; IEA:GOC. GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |