| Tag | Content |
|---|
| CPLM ID | CPLM-018759 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane protein 176B |
Protein Synonyms/Alias | Protein LR8; Tolerance-related and induced transcript protein |
Gene Name | Tmem176b |
Gene Synonyms/Alias | Lr8; Torid |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 243 | NDEETEKKLLGGDSA | ubiquitination | [1] | | 256 | SAPASPTKEKIPVTP | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Required for the development of cerebellar granule cells (By similarity). May play a role in the process of maturation of dendritic cells. |
Sequence Annotation | MOD_RES 253 253 Phosphoserine (By similarity). |
Keyword | Complete proteome; Differentiation; Membrane; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 263 AA |
Protein Sequence | MAQATVTVDG VKVTSTRPQS AQISIHIHHK SALEQLLGAM GSLKKFLSYP QARIHYGQLS 60
LGVTQILLGL VSCVLGVCLY FGPWTELCAS GCAFWSGSVA ILAGVGIVIH EMGQGKLSGH 120
ISRLLLLACS ATAAAATVMG VKSLIWQTSA SYYFEISSTC DSLQPSIVDR FRSVRFTDDS 180
DWRTERCREY LRMMMNLFLA FCILFTVICI LKIVVSVASL GLSLRSMCGR NSQVLNDEET 240
EKKLLGGDSA PASPTKEKIP VTP 263 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:2001199; P:negative regulation of dendritic cell differentiation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |