| Tag | Content |
|---|
| CPLM ID | CPLM-016356 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | N-acetylglucosamine-6-sulfatase |
Protein Synonyms/Alias | Glucosamine-6-sulfatase; G6S |
Gene Name | Gns |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 129 | YTFPAILKSVCGYQT | acetylation | [1] | | 297 | SVDDLVEKLVKRLDS | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | |
Sequence Annotation | METAL 47 47 Calcium (By similarity).
METAL 48 48 Calcium (By similarity).
METAL 83 83 Calcium; via 3-oxoalanine (By
METAL 318 318 Calcium (By similarity).
METAL 319 319 Calcium (By similarity).
MOD_RES 83 83 3-oxoalanine (Cys) (By similarity).
CARBOHYD 103 103 N-linked (GlcNAc...) (Potential).
CARBOHYD 109 109 N-linked (GlcNAc...) (Potential).
CARBOHYD 175 175 N-linked (GlcNAc...) (Potential).
CARBOHYD 190 190 N-linked (GlcNAc...) (Potential).
CARBOHYD 202 202 N-linked (GlcNAc...) (Potential).
CARBOHYD 271 271 N-linked (GlcNAc...) (Potential).
CARBOHYD 354 354 N-linked (GlcNAc...) (Potential).
CARBOHYD 379 379 N-linked (GlcNAc...) (Potential).
CARBOHYD 397 397 N-linked (GlcNAc...) (Potential).
CARBOHYD 414 414 N-linked (GlcNAc...) (Potential).
CARBOHYD 441 441 N-linked (GlcNAc...) (Potential).
CARBOHYD 472 472 N-linked (GlcNAc...) (Potential). |
Keyword | Calcium; Complete proteome; Glycoprotein; Hydrolase; Lysosome; Metal-binding; Reference proteome; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 544 AA |
Protein Sequence | MRLPSAAGPR PGRPRRLPAL LLLPLLGGCL GLVGAARRPN VLLLLTDDQD AELGGMTPLK 60
KTKALIGEKG MTFSSAYVPS ALCCPSRASI LTGKYPHNHH VVNNTLEGNC SSKAWQKIQE 120
PYTFPAILKS VCGYQTFFAG KYLNEYGAPD AGGLEHIPLG WSYWYALEKN SKYYNYTLSI 180
NGKARKHGEN YSVDYLTDVL ANLSLDFLDY KSNSEPFFMM ISTPAPHSPW TAAPQYQKAF 240
QNVIAPRNKN FNIHGTNKHW LIRQAKTPMT NSSIRFLDDA FRRRWQTLLS VDDLVEKLVK 300
RLDSTGELDN TYIFYTSDNG YHTGQFSLPI DKRQLYEFDI KVPLLVRGPG IKPNQTSKML 360
VSNIDLGPTI LDLAGYDLNK TQMDGMSLLP ILKGDRNLTW RSDVLVEYQG EGRNVTDPTC 420
PSLSPGVSQC FPDCVCEDAY NNTYACVRTL SSLWNLQYCE FDDQEVFVEV YNITADPDQI 480
TNIAKSIDPE LLGKMNYRLM MLQSCSGPTC RTPGVFDPGY RFDLRLMFNS HGSVRTRRFS 540
KHPL 544 |
Gene Ontology | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IEA:EC. GO:0008484; F:sulfuric ester hydrolase activity; ISO:MGI. GO:0030203; P:glycosaminoglycan metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |