CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DMWD protein 
Protein Synonyms/Alias
 Dystrophia myotonica-containing WD repeat motif 
Gene Name
 DMWD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
248GSGSGGEKPSGPVPRubiquitination[1]
318CTWARPGKAGISSQPubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
MLLRGLMKSY FGGLLCVCWS PDGRYVVTGG EDDLVTVWSF TEGRVVARGH GHKSWVNAVA 60
FDPYTTRAEE AATAAGADGE RSGEEEEEEP EAAGTGSAGG APLSPLPKAG SITYRFGSAG 120
QDTQFCLWDL TEDVLYPHPP LARTRTLPGT PGTTPPAASS SRGGEPGPGP LPRSLSRSNS 180
LPHPAGGGKA GGPGVAAEPG TPFSIGRFAT LTLQERRDRG AEKEHKRYHS LGNISRGGSG 240
GSGSGGEKPS GPVPRSRLDP AKVLGTALCP RIHEVPLLEP LVCKKIAQER LTVLLFLEDC 300
IITACQEGLI CTWARPGKAG ISSQPGNSPS GTVV 334 
Gene Ontology
  
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS