CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017810
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Niban-like protein 1 
Protein Synonyms/Alias
 Protein FAM129B 
Gene Name
 Fam129b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
104GLVLYENKVAYERQIubiquitination[1]
401QLAYHPLKMQSCYEKacetylation[2]
401QLAYHPLKMQSCYEKubiquitination[1]
408KMQSCYEKMEPLRLDacetylation[2]
430VSSTSVFKQRAQIHMubiquitination[1]
479ILERVLKKYDYDSSSacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
 May play a role in apoptosis suppression (By similarity). 
Sequence Annotation
 DOMAIN 68 192 PH.
 MOD_RES 568 568 Phosphoserine (By similarity).
 MOD_RES 574 574 Phosphoserine (By similarity).
 MOD_RES 607 607 Phosphoserine (By similarity).
 MOD_RES 628 628 Phosphoserine (By similarity).
 MOD_RES 650 650 Phosphoserine (By similarity).
 MOD_RES 669 669 Phosphoserine (By similarity).
 MOD_RES 685 685 Phosphoserine (By similarity).
 MOD_RES 695 695 Phosphoserine (By similarity).
 MOD_RES 699 699 Phosphoserine (By similarity).  
Keyword
 Cell junction; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 749 AA 
Protein Sequence
MGDVLSTHLD DARRQHIAEK TEKILTEFLR FYEDQYGVSL FNSMRHEIEG TGPPQAQLLW 60
RKVPLDERII FSGNLFQYQE DNKKWRNRFS LVPHNYGLVL YENKVAYERQ IPPRAVINSA 120
GYKVLTSVDQ YLELVGNSLP GTTSKSGSTP ILKCPTQFPL ILWHPYARHY YFCMMTEAEQ 180
DKWQAVLQDC VRHCNNGIPE NSKVEGPAFT DAIRMYRQSK EQYGTWEMLC GNEVQILSNL 240
VMEELGPALK AELGPRLKGK PQERQRQWIQ ISDAVYRLVF EQAKVHFEDV LCKLQRARPA 300
MEAVIRTDMD QIITSKEHLA SKIRAFILPK AEVCVRNHVQ PYIPSILEAL MVPTSQGFTE 360
VRDVFFKEVT DMNLNVINEG GIDKLGEYME KLSQLAYHPL KMQSCYEKME PLRLDGLQQR 420
FDVSSTSVFK QRAQIHMREQ MDNAVYTFET LLHQELGKGP TKEELCKSIQ RILERVLKKY 480
DYDSSSVRKR FFREALLQIT IPFLLKKLAP TCKSELPRFQ ELIFEDFARF ILVENTYEEV 540
VLQTVMKDIL QAVKEAAVQR KHNLYRDSMV LHNSDPNLHL LAEGTPIDWG EQYGDSGDSG 600
GGDSGGSPCP SEAATLTEKR RRAKQVMSVV QDEESGLPFE AGVEPPSPAS PDSVTELRGL 660
LAQDLQAESS PPASPLLNGA PVQESSQPVA VPEASPPASP LRHLPPGKAV DLEPPKPSDQ 720
ETGEQVSSPG SRPPIHTTTE DSAGVQTEF 749 
Gene Ontology
 GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara. 
Interpro
 IPR026088; Niban_like.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
  
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS