CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043401
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Obscurin 
Protein Synonyms/Alias
  
Gene Name
 OBSCN 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8915KRRALLYKRHNLAQVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Disulfide bond; Immunoglobulin domain; Kinase; Nucleotide-binding; Reference proteome; Repeat; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 8923 AA 
Protein Sequence
MDQPQFSGAP RFLTRPKAFV VSVGKDATLS CQIVGNPTPQ VSWEKDQQPV AAGARFRLAQ 60
DGDLYRLTIL DLALGDSGQY VCRARNAIGE AFAAVGLQVD AEAACAEQAP HFLLRPTSIR 120
VREGSEATFR CRVGGSPRPA VSWSKDGRRL GEPDGPRVRV EELGEASALR IRAARPRDGG 180
TYEVRAENPL GAASAAAALV VDSDAADTAS RPGTSTAALL AHLQRRREAM RAEGAPASPP 240
STGTRTCTVT EGKHARLSCY VTGEPKPETV WKKDGQLVTE GRRHVVYEDA QENFVLKILF 300
CKQSDRGLYT CTASNLVGQT YSSVLVVVRE PAVPFKKRLQ DLEVREKESA TFLCEVPQPS 360
TEAAWFKEET RLWASAKYGI EEEGTERRLT VRNVSADDDA VYICETPEGS RTVAELAVQG 420
NLLRKLPRKT AVRVGDTAMF CVELAVPVGP VHWLRNQEEV VAGGRVAISA EGTRHTLTIS 480
QCCLEDVGQV AFMAGDCQTS TQFCVSAPRK PPLQPPVDPV VKARMESSVI LSWSPPPHGE 540
RPVTIDGYLV EKKKLGTYTW IRCHEAEWVA TPELTVADVA EEGNFQFRVS ALNSFGQSPY 600
LEFPGTVHLA PKLAVRTPLK AVQAVEGGEV TFSVDLTVAS AGEWFLDGQA LKASSVYEIH 660
CDRTRHTLTI REVPASLHGA QLKFVANGIE SSIRMEVRAA PGLTANKPPA AAAREVLARL 720
HEEAQLLAEL SDQAAAVTWL KDGRTLSPGP KYEVQASAGR RVLLVRDVAR DDAGLYECVS 780
RGGRIAYQLS VQGLARFLHK DMAGSCVDAV AGGPAQFECE TSEAHVHVHW YKDGMELGHS 840
GERFLQEDVG TRHRLVAATV TRQDEGTYSC RVGEDSVDFR LRVSEPKAVF AKEQPACREV 900
QAEVGASATL SCEVAQDQME VTWYKDGKKL SSSSKVHVEA VGCMRRLVVQ QVGQADSGEY 960
SCEARGQRVS FRLDVAEPKV VFAKEQLARR KLQAEAGASA TLSCEVAQAQ TEVTWYKDGK 1020
KLSSSSKVCM EATGCTRRLV VQQAGQADAG EYSCEAGGQR LSFHLDVKEP KVVFAKDQVA 1080
HSEVQAEAGA SATLSCEVAQ AQTEVMWYKD GKKLSSSLKV HVEAKGCRRR LVVQQAGKTD 1140
AGDYSCEARG QRVSFRLHIT EPKMMFAKEQ SVHNEVQAEA GASAMLSCEV AQAQTEVTWY 1200
KDGKKLSSSS KVGMEVKGCT RRLVLPQAGK ADAGEYSCEA GGQRVSFHLH ITEPKGVFAK 1260
EQSVHNEVQA EAGTTAMLSC EVAQPQTEVT WYKDGKKLSS SSKVRMEVKG CTRRLVVQQV 1320
GKADAGEYSC EAGGQRVSFQ LHITEPKAVF AKEQLVHNEV RTEAGASATL SCEVAQAQTE 1380
VTWYKDGKKL SSSSKVRIEA AGCMRQLVVQ QAGQADAGEY TCEAGGQRLS FHLDVSEPKA 1440
VFAKEQLAHR KVQAEAGAIA TLSCEVAQAQ TEVTWYKDGK KLSSSSKVRM EAVGCTRRLV 1500
VQQACQADTG EYSCEAGGQR LSFSLDVAEP KVVFAKEQPV HREVQAQAGA STTLSCEVAQ 1560
AQTEVMWYKD GKKLSFSSKV RMEAVGCTRR LVVQQAGQAV AGEYSCEAGS QRLSFHLHVA 1620
EPKAVFAKEQ PAHREVQAEA GASATLSCEV AQAQTEVTWY KDGKKLSSSL KVHVEAAGCT 1680
RRLVVQQAGQ ADTGEYSCEA GGQQLSFRLQ VAEPKAVFAK EQPASREVQA EAGTSATLSC 1740
EVAQAQTEVT WYKDGKKLSS SSKVRMEAVG CTRRLVVQEA GQADAGEYSC KAGDQRLSFH 1800
LHVAEPKVVF AKEQPAHREV QAEAGASATL SCEVAQAQTE VTWYKDGKKL SSSSKVRVEA 1860
VGCTRRLVVQ QAGQAEAGEY SCEAGGQQLS FRLQVAEPKA VFAKEQVVFA KDQPVHREVQ 1920
AEAGTSTMLS CEVAQAQTEV MWYKDGKKLS SSSKMRVEAV GCTRRLVVQE AGQADAGEYS 1980
CEAGGQRLSF HLHVAEPKVV FAKEQPACRE VQAEAGASAT LSCEVAQGQM EVTWYKDGKK 2040
LSSSSKVHME ASGYTRRLVV QQAGQADAGE YSCEAGGQRL SFRLHVAELE PQISERPCRR 2100
EPLVVKEHED IILTATLATP SAATVTWLKD GVEIRRSKRH ETASQGDTHT LTVHGAQVLD 2160
SAIYSCRVGA EGQDFPVQVE EVAAKFCRLL EPVCGELGGT VTLACELSPA CAEVVWRCGN 2220
TQLRVGKRFQ MVAEGPVRSL TVLGLRAEDA GEYVCESRDD HTSAQLTVSV PRVVKFMSGL 2280
STVVAEEGGE ATFQCVVSPS DVAVVWFRDG ALLQPSEKFA ISQSGASHSL TISDLVLEDA 2340
GQITVEAEGA SSSAALRVRE APVLFKKKLE PQTVEERSSV TLEVELTRPW PELRWTRNAT 2400
ALAPGKNVEI HAEGARHRLV LHNVGFADRG FFGCETPDDK TQAKLTVEMR QVRLVRGLQA 2460
VEAREQGTAT MEVQLSHADV DGSWTRDGLR FQQGPTCHLA VRGPMHTLTL SGLRPEDSGL 2520
MVFKAEGVHT SARLVVTELP VSFSRPLQDV VTTEKEKVTL ECELSRPNVD VRWLKDGVEL 2580
RAGKTMAIAA QGACRSLTIY RCEFADQGVY VCDAHDAQSS ASVKVQGRNI QIVRPLEDVE 2640
VMEKDGATFS CEVSHDEVPG QWFWEGSKLR PTDNVRIRQE GRTYTLIYRR VLAEDAGEIQ 2700
FVAENAESRA QLRVKELPVT LVRPLRDKIA MEKHRGVLEC QVSRASAQVR WFKGSQELQP 2760
GPKYELVSDG LYRKLIISDV HAEDEDTYTC DAGDVKTSAQ FFVEEQSITI VRGLQDVTVM 2820
EPAPAWFECE TSIPSVRPPK WLLGKTVLQA GGNVGLEQEG TVHRLMLRRT CSTMTGPVHF 2880
TVGKSRSSAR LVVSDIPVVL TRPLEPKTGR ELQSVVLSCD FRPAPKAVQW YKDDTPLSPS 2940
EKFKMSLEGQ MAELRILRLM PADAGVYRCQ AGSAHSSTEV TVEAREVTVT GPLQDAEATE 3000
EGWASFSCEL SHEDEEVEWS LNGMPLYNDS FHEISHKGRR HTLVLKSIQR ADAGIVRASS 3060
LKVSTSARLE VRVKPVVFLK ALDDLSAEER GTLALQCEVS DPEAHVVWRK DGVQLGPSDK 3120
YDFLHTAGTR GLVVHDVSPE DAGLYTCHVG SEETRARVRV HDLHVGITKR LKTMEVLEGE 3180
SCSFECVLSH ESASDPAMWT VGGKTVGSSS RFQATRQGRK YILVVREAAP SDAGEVVFSV 3240
RGLTSKASLI VRERPAAIIK PLEDQWVAPG EDVELRCELS RAGTPVHWLK DRKAIRKSQK 3300
YDVVCEGTMA MLVIRGASLK DAGEYTCEVE ASKSTASLHV EEKANCFTEE LTNLQVEEKG 3360
TAVFTCKTEH PAATVTWRKG LLELRASGKH QPSQEGLTLR LTISALEKAD SDTYTCDIGQ 3420
AQSRAQLLVQ GRRVHIIEDL EDVDVQEGSS ATFRCRISPA NYEPVHWFLD KTPLHANELN 3480
EIDAQPGGYH VLTLRQLALK DSGTIYFEAG DQRASAALRV TEKPSVFSRE LTDATITEGE 3540
DLTLVCETST CDIPVCWTKD GKTLRGSARC QLSHEGHRAQ LLITGATLQD SGRYKCEAGG 3600
ACSSSIVRVH ARPVRFQEAL KDLEVLEGGA ATLRCVLSSV AAPVKWCYGN NVLRPGDKYS 3660
LRQEGAMLEL VVRNLRPQDS GRYSCSFGDQ TTSATLTVTA LPAQFIGKLR NKEATEGATA 3720
TLRCELSKAA PVEWRKGSET LRDGDRYCLR QDGAMCELQI RGLAMVDAAE YSCVCGEERT 3780
SASLTIRPMP AHFIGRLRHQ ESIEGATATL RCELSKAAPV EWRKGRESLR DGDRHSLRQD 3840
GAVCELQICG LAVADAGEYS CVCGEERTSA TLTVKALPAK FTEGLRNEEA VEGATAMLWC 3900
ELSKVAPVEW RKGPENLRDG DRYILRQEGT RCELQICGLA MADAGEYLCV CGQERTSATL 3960
TIRALPARFI EDVKNQEARE GATAVLQCEL NSAAPVEWRK GSETLRDGDR YSLRQDGTKC 4020
ELQIRGLAMA DTGEYSCVCG QERTSAMLTV RALPIKFTEG LRNEEATEGA TAVLRCELSK 4080
MAPVEWWKGH ETLRDGDRHS LRQDGARCEL QIRGLVAEDA GEYLCMCGKE RTSAMLTVRA 4140
MPSKFIEGLR NEEATEGDTA TLWCELSKAA PVEWRKGHET LRDGDRHSLR QDGSRCELQI 4200
RGLAVVDAGE YSCVCGQERT SATLTVRALP ARFIEDVKNQ EAREGATAVL QCELSKAAPV 4260
EWRKGSETLR GGDRYSLRQD GTRCELQIHG LSVADTGEYS CVCGQERTSA TLTVRALPAR 4320
FTQDLKTKEA SEGATATLQC ELSKVAPVEW KKGPETLRDG GRYSLKQDGT RCELQIHDLS 4380
VADAGEYSCM CGQERTSATL TVRALPARFT EGLRNEEAME GATATLQCEL SKAAPVEWRK 4440
GLEALRDGDK YSLRQDGAVC ELQIHGLAMA DNGVYSCVCG QERTSATLTV RALPARFIED 4500
MRNQKATEGA TVTLQCKLRK AAPVEWRKGP NTLKDGDRYS LKQDGTSCEL QIRGLVIADA 4560
GEYSCICEQE RTSATLTVRA LPARFIEDVR NHEATEGATA VLQCELSKAA PVEWRKGSET 4620
LRDGDRYSLR QDGTRCELQI RGLAVEDTGE YLCVCGQERT SATLTVRALP ARFIDNMTNQ 4680
EAREGATATL HCELSKVAPV EWRKGPETLR DGDRHSLRQD GTRCELQIRG LSVADAGEYS 4740
CVCGQERTSA TLTIRALPAK FTKGLRNEEA TEGATAMLQC ELSKVAPVEW RKGPETLRDG 4800
DRYNLRQDGT RCELQIHGLS VADTGEYSCV CGQEKTSATL TVKAPQPVFR EPLQSLQAEE 4860
GSTATLQCEL SEPTATVVWS KGGLQLQANG RREPRLQGCT AELVLQDLQR EDTGEYTCTC 4920
GSQATSATLT VTAAPVRFLR ELQHQEVDEG GTAHLCCELS RAGASVEWRK GSLQLFPCAK 4980
YQMVQDGAAA ELLVRGVEQE DAGDYTCDTG HTQSMASLSV RVPRPKFKTR LQSLEQETGD 5040
IARLCCQLSD AESGAVVQWL KEGVELHAGP KYEMRSQGAT RELLIHQLEA KDTGEYACVT 5100
GGQKTAASLR VTEPEVTIVR GLVDAEVTAD EDVEFSCEVS RAGATGVQWC LQGLPLQSNE 5160
VTEVAVRDGR IHTLRLKGVT PEDAGTVSFH LGNHASSAQL TVRAPEVTIL EPLQDVQLSE 5220
GQDASFQCRL SRASGQEARW ALGGVPLQAN EMNDITVEQG TLHLLTLHKV TLEDAGTVSF 5280
HVGTCSSEAQ LKVTAKNTVV RGLENVEALE GGEALFECQL SQPEVAAHTW LLDDEPVHTS 5340
ENAEVVFFEN GLRHLLLLKN LRPQDSCRVT FLAGDMVTSA FLTVRGWRLE ILEPLKNAAV 5400
RAGAQACFTC TLSEAVPVGE ASWYINGAAV QPDDSDWTVT ADGSHHALLL RSAQPHHAGE 5460
VTFACRDAVA SARLTVLGLP DPPEDAEVVA RSSHTVTLSW AAPMSDGGGG LCGYRVEVKE 5520
GATGQWRLCH ELVPGPECVV DGLAPGETYR FRVAAVGPVG AGEPVHLPQT VRLAEPPKPV 5580
PPQPSAPESR QVAAGEDVSL ELEVVAEAGE VIWHKGMERI QPGGRFEVVS QGRQQMLVIK 5640
GFTAEDQGEY HCGLAQGSIC PAAATFQVAL SPASVDEAPQ PSLPPEAAQE GDLHLLWEAL 5700
ARKRRMSREP TLDSISELPE EDGRSQRLPQ EAEEVAPDLS EGYSTADELA RTGDADLSHT 5760
SSDDESRAGT PSLVTYLKKA GRPGTSPLAS KVGAPAAPSV KPQQQQEPLA AVRPPLGDLS 5820
TKDLGDPSMD KAAVKIQAAF KGYKVRKEMK QQEGPMFSHT FGDTEAQVGD ALRLECVVAS 5880
KADVRARWLK DGVELTDGRH HHIDQLGDGT CSLLITGLDR ADAGCYTCQV SNKFGQVTHS 5940
ACVVVSGSES EAESSSGGEL DDAFRRAARR LHRLFRTKSP AEVSDEELFL SADEGPAEPE 6000
EPADWQTYRE DEHFICIRFE ALTEARQAVT RFQEMFATLG IGVEIKLVEQ GPRRVEMCIS 6060
KETPAPVVPP EPLPSLLTSD AAPVFLTELQ NQEVQDGYPV SFDCVVTGQP MPSVRWFKDG 6120
KLLEEDDHYM INEDQQGGHQ LIITAVVPAD MGVYRCLAEN SMGVSSTKAE LRVDLTSTDY 6180
DTAADATESS SYFSAQGYLS SREQEGTEST TDEGQLPQVV EELRDLQVAP GTRLAKFQLK 6240
VKGYPAPRLY WFKDGQPLTA SAHIRMTDKK ILHTLEIISV TREDSGQYAA YISNAMGAAY 6300
SSARLLVRGP DEPEEKPASD VHEQLVPPRM LERFTPKKVK KGSSITFSVK VEGRPVPTVH 6360
WLREEAERGV LWIGPDTPGY TVASSAQQHS LVLLDVGRQH QGTYTCIASN AAGQALCSAS 6420
LHVSGLPKVE EQEKVKEALI STFLQGTTQA ISAQGLETAS FADLGGQRKE EPLAAKEALG 6480
HLSLAEVGTE EFLQKLTSQI TEMVSAKITQ AKLQVPGGDS DEDSKTPSAS PRHGRSRPSS 6540
SIQESSSESE DGDARGEIFD IYVVTADYLP LGAEQDAITL REGQYVEVLD AAHPLRWLVR 6600
TKPTKSSPSR QGWVSPAYLD RRLKLSPEWG AAEAPEFPGE AVSEDEYKAR LSSVIQELLS 6660
SEQAFVEELQ FLQSHHLQHL ERCPHVPIAV AGQKAVIFRN VRDIGRFHSS FLQELQQCDT 6720
DDDVAMCFIK NQAAFEQYLE FLVGRVQAES VVVSTAIQEF YKKYAEEALL AGDPSQPPPP 6780
PLQHYLEQPV ERVQRYQALL KELIRNKARN RQNCALLEQA YAVVSALPQR AENKLHVSLM 6840
ENYPGTLQAL GEPIRQGHFI VWEGAPGARM PWKGHNRHVF LFRNHLVICK PRRDSRTDTV 6900
SYVFRNMMKL SSIDLNDQVE GDDRAFEVWQ EREDSVRKYL LQARTAIIKS SWVKEICGIQ 6960
QRLALPVWRP PDFEEELADC TAELGETVKL ACRVTGTPKP VISWYKDGKA VQVDPHHILI 7020
EDPDGSCALI LDSLTGVDSG QYMCFAASAA GNCSTLGKIL VQVPPRFVNK VRASPFVEGE 7080
DAQFTCTIEG APYPQIRWYK DGALLTTGNK FQTLSEPRSG LLVLVIRAAS KEDLGLYECE 7140
LVNRLGSARA SAELRIQSPM LQAQEQCHRE QLVAAVEDTT LERADQEVTS VLKRLLGPKA 7200
PGPSTGDLTG PGPCPRGAPA LQETGSQPPV TGTSEAPAVP PRVPQPLLHE GPEQEPEAIA 7260
RAQEWTVPIR MEGAAWPGAG TGELLWDVHS HVVRETTQRT YTYQAIDTHT ARPPSMQVTI 7320
EDVQAQTGGT AQFEAIIEGD PQPSVTWYKD SVQLVDSTRL SQQQEGTTYS LVLRHVASKD 7380
AGVYTCLAQN TGGQVLCKAE LLVLGGDNEP DSEKQSHRRK LHSFYEVKEE IGRGVFGFVK 7440
RVQHKGNKIL CAAKFIPLRS RTRAQAYRER DILAALSHPL VTGLLDQFET RKTLILILEL 7500
CSSEELLDRL YRKGVVTEAE VKVYIQQLVE GLHYLHSHGV LHLDIKPSNI LMVHPAREDI 7560
KICDFGFAQN ITPAELQFSQ YGSPEFVSPE IIQQNPVSEA SDIWAMGVIS YLSLTCSSPF 7620
AGESDRATLL NVLEGRVSWS SPMAAHLSED AKDFIKATLQ RAPQARPSAA QCLSHPWFLK 7680
SMPAEEAHFI NTKQLKFLLA RSRWQRSLMS YKSILVMRSI PELLRGPPDS PSLGVARHLC 7740
RDTGGSSSSS SSSDNELAPF ARAKSLPPSP VTHSPLLHPR GFLRPSASLP EEAEASERST 7800
EAPAPPASPE GAGPPAAQGC VPRHSVIRSL FYHQAGESPE HGALAPGSRR HPARRRHLLK 7860
GGYIAGALPG LREPLMEHRV LEEEAAREEQ ATLLAKAPSF ETALRLPASG THLAPGHSHS 7920
LEHDSPSTPR PSSEACGEAQ RLPSAPSGGA PIRDMGHPQG SKQLPSTGGH PGTAQPERPS 7980
PDSPWGQPAP FCHPKQGSAP QEGCSPHPAV APCPPGSFPP GSCKEAPLVP SSPFLGQPQA 8040
PPAPAKASPP LDSKMGPGDI SLPGRPKPGP CSSPGSASQA SSSQVSSLRV GSSQVGTEPG 8100
PSLDAEGWTQ EAEDLSDSTP TLQRPQEQAT MRKFSLGGRG GYAGVAGYGT FAFGGDAGGM 8160
LGQGPMWARI AWAVSQSEEE EQEEARAESQ SEEQQEARAE SPLPQVSARP VPEVGRAPTR 8220
SSPEPTPWED IGQVSLVQIR DLSGDAEAAD TISLDISEVD PAYLNLSDLY DIKYLPFEFM 8280
IFRKVPKSAQ PEPPSPMAEE ELAEFPEPTW PWPGELGPHA GLEITEESED VDALLAEAAV 8340
GRKRKWSSPS RSLFHFPGRH LPLDEPAELG LRERVKASVE HISRILKGRP EGLEKEGPPR 8400
KKPGLASFRL SGLKSWDRAP TFLRELSDET VVLGQSVTLA CQVSAQPAAQ ATWSKDGAPL 8460
ESSSRVLISA TLKNFQLLTI LVVVAEDLGV YTCSVSNALG TVTTTGVLRK AERPSSSPCP 8520
DIGEVYADGV LLVWKPVESY GPVTYIVQCS LEGGSWTTLA SDIFDCCYLT SKLSRGGTYT 8580
FRTACVSKAG MGPYSSPSEQ VLLGGPSHLA SEEESQGRSA QPLPSTKTFA FQTQIQRGRF 8640
SVVRQCWEKA SGRALAAKII PYHPKDKTAV LREYEALKGL RHPHLAQLHA AYLSPRHLVL 8700
ILELCSGPEL LPCLAERASY SESEVKDYLW QMLSATQYLH NQHILHLDLR SENMIITEYN 8760
LLKVVDLGNA QSLSQEKVLP SDKFKDYLET MELLEGQGAV PQTDIWAIGV TAFIMLSAEY 8820
PVSSEGARDL QRGLRKGLVR LSRCYAGLSG GAVAFLRSTL CAQPWGRPCA SSCLQCPWLT 8880
EEGPACSRPA PVTFPTARLR VFVRNREKRR ALLYKRHNLA QVR 8923 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
 GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
 GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. 
Interpro
 IPR000219; DH-domain.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR011009; Kinase-like_dom.
 IPR020675; Myosin_light_ch_kinase-rel.
 IPR020682; Obscurin-myosin_light-ch_kin.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS.
 IPR001452; SH3_domain.
 IPR008266; Tyr_kinase_AS. 
Pfam
 PF00041; fn3
 PF07679; I-set
 PF00612; IQ
 PF00069; Pkinase
 PF00621; RhoGEF 
SMART
 SM00060; FN3
 SM00409; IG
 SM00408; IGc2
 SM00015; IQ
 SM00233; PH
 SM00220; S_TKc
 SM00326; SH3 
PROSITE
 PS50010; DH_2
 PS50853; FN3
 PS50835; IG_LIKE
 PS50096; IQ
 PS50003; PH_DOMAIN
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST
 PS00109; PROTEIN_KINASE_TYR 
PRINTS