CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045407
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ECH1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
249PVAVQSTKVNLLYSRubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 267 AA 
Protein Sequence
XIVASRRLRD LLTRRLTGSN YPGLSISLRL TGSSAQEEAS GVALGEAPDH SYESLRVTSA 60
QKHVLHVQLN RPNKRNAMNK VFWREMVECF NKISRDADCR AVVISGAGKM FTAGIDLMDM 120
ASDILQPKGD DVARISWYLR DIITRYQETF NVIERCPKPV IAAVHGGCIG GGVDLVTACD 180
IRYCAQDAFF QVKEVDVGLA ADVGTLQRLP KVIGNQSRVF PDKEVMLDAA LALAAEISSK 240
SPVAVQSTKV NLLYSRDHSV AESLNYV 267 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR014748; Crontonase_C.
 IPR001753; Crotonase_core_superfam.
 IPR018376; Enoyl-CoA_hyd/isom_CS. 
Pfam
 PF00378; ECH 
SMART
  
PROSITE
 PS00166; ENOYL_COA_HYDRATASE 
PRINTS