CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014013
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 18 
Protein Synonyms/Alias
 Sarcoma antigen NY-SAR-24 
Gene Name
 CCDC18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63PNPSRSEKLILDVQPubiquitination[1]
96GSSTDFQKKPRDKMFubiquitination[1]
101FQKKPRDKMFSSSAPubiquitination[1]
357KDEILRDKFSLMNENubiquitination[1]
405IISQLPLKRELFGFKubiquitination[1]
412KRELFGFKSYLSKYQubiquitination[1]
426QMSSFSNKEDRCIGCubiquitination[1]
457IKEAEIQKLHANLTAubiquitination[1]
482NDSQESSKLSSLETEubiquitination[1]
637CLAFEKAKKIHLEQHubiquitination[1]
660RLEAQLEKKDQQFKEubiquitination[1]
1003KMEIEDKKQELLEMDacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1454 AA 
Protein Sequence
MESSSSDYYN KDNEEESLLA NVASLRHELK ITEWSLQSLG EELSSVSPSE NSDYAPNPSR 60
SEKLILDVQP SHPGLLNYSP YENVCKISGS STDFQKKPRD KMFSSSAPVD QEIKSLREKL 120
NKLRQQNACL VTQNHSLMTK FESIHFELTQ SRAKVSMLES AQQQAASVPI LEEQIINLEA 180
EVSAQDKVLR EAENKLEQSQ KMVIEKEQSL QESKEECIKL KVDLLEQTKQ GKRAERQRNE 240
ALYNAEELSK AFQQYKKKVA EKLEKVQAEE EILERNLTNC EKENKRLQER CGLYKSELEI 300
LKEKLRQLKE ENNNGKEKLR IMAVKNSEVM AQLTESRQSI LKLESELENK DEILRDKFSL 360
MNENRELKVR VAAQNERLDL CQQEIESSRV ELRSLEKIIS QLPLKRELFG FKSYLSKYQM 420
SSFSNKEDRC IGCCEANKLV ISELRIKLAI KEAEIQKLHA NLTANQLSQS LITCNDSQES 480
SKLSSLETEP VKLGGHQVES VKDQNQHTMN KQYEKERQRL VTGIEELRTK LIQIEAENSD 540
LKVNMAHRTS QFQLIQEELL EKASNSSKLE SEMTKKCSQL LTLEKQLEEK IVAYSSIAAK 600
NAELEQELME KNEKIRSLET NINTEHEKIC LAFEKAKKIH LEQHKEMEKQ IERLEAQLEK 660
KDQQFKEQEK TMSMLQQDII CKQHHLESLD RLLTESKGEM KKENMKKDEA LKALQNQVSE 720
ETIKVRQLDS ALEICKEELV LHLNQLEGNK EKFEKQLKKK SEEVYCLQKE LKIKNHSLQE 780
TSEQNVILQH TLQQQQQMLQ QETIRNGELE DTQTKLEKQV SKLEQELQKQ RESSAEKLRK 840
MEEKCESAAH EADLKRQKVI ELTGTARQVK IEMDQYKEEL SKMEKEIMHL KRDGENKAMH 900
LSQLDMILDQ TKTELEKKTN AVKELEKLQH STETELTEAL QKREVLETEL QNAHGELKST 960
LRQLQELRDV LQKAQLSLEE KYTTIKDLTA ELRECKMEIE DKKQELLEMD QALKERNWEL 1020
KQRAAQVTHL DMTIREHRGE MEQKIIKLEG TLEKSELELK ECNKQIESLN DKLQNAKEQL 1080
REKEFIMLQN EQEISQLKKE IERTQQRMKE MESVMKEQEQ YIATQYKEAI DLGQELRLTR 1140
EQVQNSHTEL AEARHQQVQA QREIERLSSE LEDMKQLSKE KDAHGNHLAE ELGASKVREA 1200
HLEARMQAEI KKLSAEVESL KEAYHMEMIS HQENHAKWKI SADSQKSSVQ QLNEQLEKAK 1260
LELEEAQDTV SNLHQQVQDR NEVIEAANEA LLTKESELTR LQAKISGHEK AEDIKFLPAP 1320
FTSPTEIMPD VQDPKFAKCF HTSFSKCTKL RRSISASDLT FKIHGDEDLS EELLQDLKKM 1380
QLEQPSTLEE SHKNLTYTQP DSFKPLTYNL EADSSENNDF NTLSGMLRYI NKEVRLLKKS 1440
SMQTGAGLNQ GENV 1454 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS