CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013888
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trigger factor 
Protein Synonyms/Alias
 TF; PPIase 
Gene Name
 tig 
Gene Synonyms/Alias
 TTHA0614 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
32ASYEALLKDLASRVRacetylation[1]
67EALLQDLKERLVEETacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). 
Sequence Annotation
 DOMAIN 160 225 PPIase FKBP-type.  
Keyword
 Cell cycle; Cell division; Chaperone; Complete proteome; Cytoplasm; Isomerase; Reference proteome; Rotamase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 404 AA 
Protein Sequence
MAEILERSGY LVKVRVEVPA DRVKASYEAL LKDLASRVRV PGFRPGKAPL KVVEARLGRE 60
ALLQDLKERL VEETYPEAVR ELGLSPVAAR VVEQDLSEGE GFRYVAEVEN YPEVRLPDWR 120
SFALEVSPPE VTEEMVEKAL EELRQRYAEL VPVEREAQEK DHLFVRTEEG AEFPIDLAKA 180
LPHVREALLG KKAGDVVMVP VLNDKGEKVR EVRTEVLEVK TLKLPELDEE FAKTLEAESL 240
EDLKNRVRES LKRQAERAYE EARERAFLEK LAEGLEVEIP PSMLRAEERH LLEHLAEDLY 300
RQGISLEAYL EALKEKGELE KFQEDLRKEA EKRVRIALAR EKLAEELNPE VSEEEWQAYL 360
QAAARAYGVA VQDLRRQFGE EGLARLKERL RQDKAVQEAL KALG 404 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:HAMAP.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:HAMAP.
 GO:0000413; P:protein peptidyl-prolyl isomerization; IEA:GOC.
 GO:0015031; P:protein transport; IEA:HAMAP. 
Interpro
 IPR005215; Trig_fac.
 IPR008880; Trigger_fac_C.
 IPR008881; Trigger_fac_ribosome-bd_bac.
 IPR027304; Trigger_fact/SurA_dom. 
Pfam
 PF05698; Trigger_C
 PF05697; Trigger_N 
SMART
  
PROSITE
 PS50059; FKBP_PPIASE 
PRINTS