UniProt Accession

 YEAD_ECOLI; P39173; P76233; P76913 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74850.2; BAA15577.1 

Protein Name

 Putative glucose-6-phosphate 1-epimerase 

Protein Synonyms/Alias

 Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 

Gene Name

 yeaD 

Gene Synonyms/Alias

 yzzQ; b1780; JW1769 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
3	*****MIKKIFALPV	acetylation	[1]
4	****MIKKIFALPVI	acetylation	[1, 2]
22	SPVLSRRKLDELDLI	acetylation	[1]
129	TQSEETKKFWPHDFT	acetylation	[1]
187	LGDRFIDKVNDAKEN	acetylation	[1, 2]
192	IDKVNDAKENVLTDG	acetylation	[1]
279	SETQKVTKEKPAHLA	acetylation	[1, 2]
281	TQKVTKEKPAHLAQS	acetylation	[1, 2]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

  

Sequence Annotation

 ACT_SITE 164 164 By similarity.
 ACT_SITE 267 267 By similarity.
 BINDING 74 74 Substrate (By similarity).
 BINDING 99 99 Substrate (By similarity).  

Keyword

 Complete proteome; Direct protein sequencing; Isomerase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 294 AA 

Protein Sequence

Gene Ontology

 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0047938; F:glucose-6-phosphate 1-epimerase activity; IEA:EC.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki. 

Interpro

 IPR008183; Aldose_1/G6P_1-epimerase.
 IPR025532; G6P_1-epimerase.
 IPR011013; Gal_mutarotase_SF_dom.
 IPR014718; Glyco_hydro-type_carb-bd_sub. 

Pfam

 PF01263; Aldose_epim 

SMART

  

PROSITE

  

PRINTS