| Tag | Content |
|---|
| CPLM ID | CPLM-003579 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Amidophosphoribosyltransferase |
Protein Synonyms/Alias | ATase; Glutamine phosphoribosylpyrophosphate amidotransferase; GPATase |
Gene Name | purF |
Gene Synonyms/Alias | b2312; JW2309 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 119 | RKKLFEEKRRHINTT | acetylation | [1] | | 327 | PYRQGFVKNRYVGRT | acetylation | [1] | | 488 | TLRNDDAKAVQRQNE | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | |
Sequence Annotation | DOMAIN 2 236 Glutamine amidotransferase type-2.
ACT_SITE 2 2 For GATase activity.
METAL 367 367 Magnesium.
METAL 368 368 Magnesium. |
Keyword | 3D-structure; Complete proteome; Direct protein sequencing; Glutamine amidotransferase; Glycosyltransferase; Magnesium; Metal-binding; Purine biosynthesis; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 505 AA |
Protein Sequence | MCGIVGIAGV MPVNQSIYDA LTVLQHRGQD AAGIITIDAN NCFRLRKANG LVSDVFEARH 60
MQRLQGNMGI GHVRYPTAGS SSASEAQPFY VNSPYGITLA HNGNLTNAHE LRKKLFEEKR 120
RHINTTSDSE ILLNIFASEL DNFRHYPLEA DNIFAAIAAT NRLIRGAYAC VAMIIGHGMV 180
AFRDPNGIRP LVLGKRDIDE NRTEYMVASE SVALDTLGFD FLRDVAPGEA IYITEEGQLF 240
TRQCADNPVS NPCLFEYVYF ARPDSFIDKI SVYSARVNMG TKLGEKIARE WEDLDIDVVI 300
PIPETSCDIA LEIARILGKP YRQGFVKNRY VGRTFIMPGQ QLRRKSVRRK LNANRAEFRD 360
KNVLLVDDSI VRGTTSEQII EMAREAGAKK VYLASAAPEI RFPNVYGIDM PSATELIAHG 420
REVDEIRQII GADGLIFQDL NDLIDAVRAE NPDIQQFECS VFNGVYVTKD VDQGYLDFLD 480
TLRNDDAKAV QRQNEVENLE MHNEG 505 |
Gene Ontology | GO:0005829; C:cytosol; IDA:UniProtKB. GO:0004044; F:amidophosphoribosyltransferase activity; IDA:EcoliWiki. GO:0042802; F:identical protein binding; IDA:EcoCyc. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway. GO:0006541; P:glutamine metabolic process; IDA:EcoliWiki. GO:0009116; P:nucleoside metabolic process; IEA:InterPro. GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro. GO:0006164; P:purine nucleotide biosynthetic process; IDA:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |