CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043168
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium-transporting ATPase type 2C member 1 
Protein Synonyms/Alias
  
Gene Name
 Atp2c1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
42EQVARFQKIPNVENEubiquitination[1]
223LVRCGKAKGIVIGTGubiquitination[1]
490YCTTYNSKGQTLALTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 926 AA 
Protein Sequence
MENLLPPSGF SYLKKYPLHS IRKYLSTLRS QRAEEQVARF QKIPNVENET MIPVLTSKRA 60
SELAVSEVAG LLQFKNPLIM LLLASAVISI LMRQFDDAVS ITVAIVIVVT VAFVQEYRSE 120
KSLEELSKLV PPECHCVREG KLEHTLARDL VPGDTVCLSV GDRVPADLRL FEAVDLSVDE 180
SSLTGETAPC SKVTAPQPAA NGDLASRSNI AFMGTLVRCG KAKGIVIGTG ENSEFGEVFK 240
MMQAEEAPKT PLQKSMDLLG KQLSFYSFGI IGIIMLVGWL LGKDILEMFT ISVSLAVAAI 300
PEGLPIVVTV TLALGVMRMV KKRAIVKKLP IVETLGCCNV ICSDKTGTLT KNEMTVTHIL 360
TSDGLHAEVT GVGYNQFGEV IVDGDVVHGF YNPAVSRIVE AGCVCNDAVI RNNTLMGKPT 420
EGALIALAMK MGLDGLQQDY IRKAEYPFSS EQKWMAVKCV HRTQQDRPEI CFMKGAYEQV 480
IKYCTTYNSK GQTLALTQQQ RDLYQQEKAR MGSAGLRVLA LASGPELGQL TFLGLVGIID 540
PPRTGVKEAV TTLIASGVSI KMITGDSQET AIAIASRLGL YSKTSQSVSG EEVDTMEVQH 600
LSQIVPKVAV FYRASPRHKM KIIKSLQKNG AVVAMTGDGV NDAVALKAAD IGVAMGQTGT 660
DVCKEAADMI LVDDDFQTIM SAIEEGKGIY NNIKNFVRFQ LSTSIAALTL ISLATLMNFP 720
NPLNAMQILW INIIMDGPPA QSLGVEPVDK DVIRKPPRNW KDSILTKNLI LKILVSSIII 780
VCGTLFVFWR ELRDNVITPR DTTMTFTCFV FFDMFNALSS RSQTKSVFEI GLCSNKMFCY 840
AVLGSIMGQL LVIYFPPLQK VFQTESLSIL DLLFLLGLTS SVCIVSEIIK KVERSREKVQ 900
KNAGSASSSF LEVWLWQRSG QQLVEI 926 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; TAS:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005388; F:calcium-transporting ATPase activity; TAS:MGI.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR006413; ATPase_P-typ_Ca-transp_PMR1.
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
  
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.
 PR00120; HATPASE.