CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Formin-binding protein 4 
Protein Synonyms/Alias
 Formin-binding protein 30 
Gene Name
 Fnbp4 
Gene Synonyms/Alias
 Fbp30; Kiaa1014 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
294TTAASSSKSGPVITKacetylation[1]
306ITKREVKKEVNEGIQacetylation[2]
352WRRKVICKEADPVSEacetylation[1, 2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
 DOMAIN 218 252 WW 1.
 DOMAIN 603 637 WW 2.
 MOD_RES 19 19 Phosphoserine.
 MOD_RES 120 120 Phosphoserine (By similarity).
 MOD_RES 176 176 Phosphothreonine (By similarity).
 MOD_RES 440 440 Phosphoserine (By similarity).
 MOD_RES 443 443 Phosphoserine (By similarity).
 MOD_RES 472 472 Phosphoserine (By similarity).
 MOD_RES 507 507 Phosphoserine.
 MOD_RES 516 516 Phosphoserine (By similarity).
 MOD_RES 977 977 Phosphoserine (By similarity).
 MOD_RES 978 978 Phosphoserine (By similarity).
 MOD_RES 979 979 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1031 AA 
Protein Sequence
MMGKKSRAVP GRRPILQLSP PGPRSSTPGR DPDPDPDPEA DSTAAATSQS APAAATAAAA 60
TSPAVPASAA PEDSPSEDEQ EVVVEVPNVV QNPPTPVMTT RPTAVKATGG LCLLGAYADS 120
DDDESDVSEK TAQSKEANGN QATDIDSTLA NFLAEIDAIT APQPAAPVVA SAPPPTPPRP 180
EPKEAATPAL SPTASNGSDT AQTPGWHYDT QCSLAGVEIE MGDWQEVWDE NTGCYYYWNT 240
QTNEVTWELP QYLATQVQGL QHYQPSSVTG TEAAFVVNTD MYTKERTTAA SSSKSGPVIT 300
KREVKKEVNE GIQALSNSEE ERKGVAAALL APLLPEGVKE EEERWRRKVI CKEADPVSET 360
KETSTASEET GPSIKPPEVM MDGTEDPSQE ELCSVVQSGE SEEEEEEEEQ DTLELELALE 420
RKKAELRALE EGDGSVSGSS PRSDISQPAS QDGVRRIMSK RGKWKMFVRA TSPESTSRSS 480
SKTGRDSPEN GETAIGAEDS EKIDEISDKE TEVEESSEKI KVQLAPKVEE EQDLKFQIGE 540
LANTLTSKFE FLGINRQSIS NFHMLLLQTE TRIADWREGA LNGNYLKRKL QDAAEQLKQY 600
EINATPKGWS CHWDRDHRRY FYVNEQSGES QWEFPDGEEE EESQTKEVRD ESLPKLTVKD 660
KTCTDPNSTE SSENPTGSLC KESFSGQVSS SLMPLTPFWT LLQSNVPVLQ PPLPLEMPPP 720
PPPPPESPPP PPPPPPPPPP LEDGEIQEVE MEDEGSEEPP APGTEEDTPL KPSTQTTAVT 780
SQSLVDSTAS SPPSNKAVKR KAPEMSTSVV QRSATIGSSP VLYSQSAIAA GHQAVGMAHQ 840
AVGMAHQAVS ASHAAAAGVG HQARGMSLQS NYLGLAAAPA LMSYAECSVP IGVTTPSLQP 900
AQARGTMAAP AVVEPPPPPP PPPTPTPPPP PPAPKVPPPE KTRKGKKDKA KKSKTKMPSL 960
VKKWQSIQRE LDEEDNSSSS EEDRESTAQK RIEEWKQQQL VSGLAERNAN FEALPEDWRA 1020
RLKRRKMAPS T 1031 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara. 
Interpro
 IPR001202; WW_dom. 
Pfam
 PF00397; WW 
SMART
 SM00456; WW 
PROSITE
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS