| Tag | Content |
|---|
| CPLM ID | CPLM-015613 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 51 |
Protein Synonyms/Alias | Deubiquitinating enzyme 51; Ubiquitin thioesterase 51; Ubiquitin-specific-processing protease 51 |
Gene Name | USP51 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 597 | IVACFHLKRFEHVGK | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | ZN_FING 234 294 UBP-type.
ACT_SITE 372 372 Nucleophile (By similarity).
ACT_SITE 665 665 Proton acceptor (By similarity). |
Keyword | Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 711 AA |
Protein Sequence | MAQVRETSLP SGSGVRWISG GGGGASPEEA VEKAGKMEEA AAGATKASSR REAEEMKLEP 60
LQEREPAPEE NLTWSSSGGD EKVLPSIPLR CHSSSSPVCP RRKPRPRPQP RARSRSQPGL 120
SAPPPPPARP PPPPPPPPPP APRPRAWRGS RRRSRPGSRP QTRRSCSGDL DGSGDPGGLG 180
DWLLEVEFGQ GPTGCSHVES FKVGKNWQKN LRLIYQRFVW SGTPETRKRK AKSCICHVCS 240
THMNRLHSCL SCVFFGCFTE KHIHKHAETK QHHLAVDLYH GVIYCFMCKD YVYDKDIEQI 300
AKETKEKILR LLTSTSTDVS HQQFMTSGFE DKQSTCETKE QEPKLVKPKK KRRKKSVYTV 360
GLRGLINLGN TCFMNCIVQA LTHIPLLKDF FLSDKHKCIM TSPSLCLVCE MSSLFHAMYS 420
GSRTPHIPYK LLHLIWIHAE HLAGYRQQDA HEFLIAILDV LHRHSKDDSG GQEANNPNCC 480
NCIIDQIFTG GLQSDVTCQA CHSVSTTIDP CWDISLDLPG SCATFDSQNP ERADSTVSRD 540
DHIPGIPSLT DCLQWFTRPE HLGSSAKIKC NSCQSYQEST KQLTMKKLPI VACFHLKRFE 600
HVGKQRRKIN TFISFPLELD MTPFLASTKE SRMKEGQPPT DCVPNENKYS LFAVINHHGT 660
LESGHYTSFI RQQKDQWFSC DDAIITKATI EDLLYSEGYL LFYHKQGLEK D 711 |
Gene Ontology | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |