| Tag | Content |
|---|
| CPLM ID | CPLM-021568 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial |
Protein Synonyms/Alias | Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1 |
Gene Name | RSAD1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 60 | CSYCNFNKYIPRRLE | ubiquitination | [1] | | 331 | LEPDNWMKEVMLFGH | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in porphyrin cofactor biosynthesis (By similarity). |
Sequence Annotation | REGION 99 100 S-adenosyl-L-methionine 2 binding (By
METAL 49 49 Iron-sulfur (4Fe-4S-S-AdoMet)
METAL 53 53 Iron-sulfur (4Fe-4S-S-AdoMet)
METAL 56 56 Iron-sulfur (4Fe-4S-S-AdoMet)
BINDING 43 43 S-adenosyl-L-methionine 1 (By
BINDING 55 55 S-adenosyl-L-methionine 2; via carbonyl
BINDING 98 98 S-adenosyl-L-methionine 1; via amide
BINDING 131 131 S-adenosyl-L-methionine 1 (By
BINDING 158 158 S-adenosyl-L-methionine 2 (By
BINDING 170 170 S-adenosyl-L-methionine 2 (By
BINDING 195 195 S-adenosyl-L-methionine 2 (By |
Keyword | 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding; Mitochondrion; Oxidoreductase; Polymorphism; Porphyrin biosynthesis; Reference proteome; S-adenosyl-L-methionine; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 442 AA |
Protein Sequence | MALPGARARG WAAAARAAQR RRRVENAGGS PSPEPAGRRA ALYVHWPYCE KRCSYCNFNK 60
YIPRRLEEAA MQKCLVTEAQ TLLRLSGVQR VESVFFGGGT PSLASPHTVA AVLEAVAQAA 120
HLPADLEVTL EANPTSAPGS RLAEFGAAGV NRLSIGLQSL DDTELRLLGR THSACDALRT 180
LAEARRLFPG RVSVDLMLGL PAQQVGPWLG QLQELLHHCD DHLSLYQLSL ERGTALFAQV 240
QRGALPAPDP ELAAEMYQRG RAVLREAGFH QYEVSNFARN GALSTHNWTY WQCGQYLGVG 300
PGAHGRFMPQ GAGGHTREAR IQTLEPDNWM KEVMLFGHGT RKRVPLGRLE LLEEVLALGL 360
RTDVGITHQH WQQFEPQLTL WDVFGANKEV QELLERGLLQ LDHRGLRCSW EGLAVLDSLL 420
LTLLPQLQEA WQQRTPSPVP GG 442 |
Gene Ontology | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW. GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |