| Tag | Content |
|---|
| CPLM ID | CPLM-017826 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cirhin |
Protein Synonyms/Alias | Testis-expressed gene 292 protein |
Gene Name | Cirh1a |
Gene Synonyms/Alias | Kiaa1988; Tex292 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 432 | ISLQRVSKLPSFLRS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be a transcriptional regulator (By similarity). Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (By similarity). |
Sequence Annotation | REPEAT 14 53 WD 1.
REPEAT 57 96 WD 2.
REPEAT 99 138 WD 3.
REPEAT 143 181 WD 4.
REPEAT 193 231 WD 5.
REPEAT 234 273 WD 6.
REPEAT 285 322 WD 7.
REPEAT 324 359 WD 8.
REPEAT 435 474 WD 9.
REPEAT 482 521 WD 10.
REPEAT 524 563 WD 11. |
Keyword | Complete proteome; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 686 AA |
Protein Sequence | MGEFKVHRVR FFNYVPSGIR CVAYNNQSNR LAVSRTDGTV EIYNLSANYF QEKFFPGHES 60
RGTEALCWAG GQRLFSAGLN GEILEYDLQA LNIKYTLDAF GGPIWSMTAS PSGSQLLVGC 120
EDGSVKLFEV TPEKIQFARN FDRQKSRILS LCWHPAGTHV AAGSLDYISV FDVKSGSIIR 180
KMVLDRQHLG VTKSRCIVWG VAFLSDGTVI SVDSVGKVQL WDSATGTLVK SHLVANADVQ 240
SIAVADQEDS FVVGTAEGTV FHFQLVSMTS NSSEKQWVRT KPFQHHTHDV RAVAHSPTAL 300
ISGGTDTHLV IRPLMERVEV KNYDAALRKI TFPHRRLISC SKRRQLLLFQ FAHHLELWRL 360
GSTSATGKNG DTLPLSKNAD HLLHLKTKGP ENIICSCVSP CGSWIAYSTA SRFFLYRLKY 420
ERDNISLQRV SKLPSFLRSA LHILFSEDST KLLVASNQGS LHIVHLSEGS FKHLHTFQPQ 480
SGTVEAMCLL AVSPDGNWLA ASGTSAGVHV YDLHHLKLHC TVPAYNFPVT ALAIAPNTNN 540
LVIAHSDQQV FEFSIPEKQY TEWSRSLQKQ GFHQLWLQRD TPITHISFHP KRPMHILLHD 600
AYMFCIIDKS LPLPNEKTVL YNPLPPKNES DVFLRRTTHG FKMSKIYKPL LFMDLLDERT 660
LVAVERPLDD IIAQLPPPIK KKKFGT 686 |
Gene Ontology | GO:0005730; C:nucleolus; ISS:UniProtKB. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |