UniProt Accession

 CGBP1_HUMAN; Q9UFW8; D3DU38; O15183 

Genbank Protein ID

 AJ000258; AF094481; CR456854; AL117392; AM393707; CH471110; CH471110; BC052980 

Genbank Nucleotide ID

 CAA03974.1; AAD04161.1; CAG33135.1; CAB55894.1; CAL38583.1; EAW68863.1; EAW68864.1; AAH52980.1 

Protein Name

 CGG triplet repeat-binding protein 1 

Protein Synonyms/Alias

 CGG-binding protein 1; 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein 

Gene Name

 CGGBP1 

Gene Synonyms/Alias

 CGGBP 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
71	SKTHTKRKAEFEEQN	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter. 

Sequence Annotation

 MOTIF 80 84 Nuclear localization signal (Potential).
 MOD_RES 56 56 Phosphoserine.
 MOD_RES 164 164 Phosphoserine.  

Keyword

 Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 167 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:LIFEdb.
 GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

  

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