CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038187
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Sbf2 
Protein Synonyms/Alias
  
Gene Name
 Sbf2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1675EIEKLEHKLNQTPERubiquitination[1]
1836APKYTSDKAFFDLKTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1872 AA 
Protein Sequence
MARLADYFIV VGYDHEKPAG PGEGLGKIIQ RFPQQDWDDT PFPQGIELFC QPGGWHLSRE 60
RKQPTFFVVV LTDIDSDRHY CSCLTFYEAE INLQGTKKEE IEGEEVSGLI QPAEVFAPKS 120
LVLVSRLDYP EIFRACLGLI YTVYVDSMSV SLESLIANLC ACLVPAAGGS QKLFSLGAGD 180
RQLIQTPLHD SLPVTGTSVA LLFQQLGIQN VLNLFCAVLT ENKVLFHSAS FQRLSDACRA 240
LESLMFPLKY SYPYIPILPA QLLEVLSSPT PFIIGVHSIF KTDVHELLDV IIADLDGGTI 300
KIPECIHLSS LPEPLLHQTQ SALSLILHPD LEVADHAFPP PRTALSHSKM LDKEVRAVFL 360
RLFAQLFQGY RSCLQLIRIH AEPVIHFHKT AFLGQRGLVE NDFLTKVLNG MAFAGFVSER 420
GPPYRACDLF DELVAFEVER IKVEEKNPLK MIKHIRELAE QLFKNENPNP HMAFQKVPRP 480
TEGSHLRVHI LPFPKINEAR VQELIQENLA KNQNAPPATR IEKKCVVPAG PPVVSIMEKV 540
ITVFNSAQRL EVVRNCISFI FENKTLETEK TLPAALRALK GKAARQCLTD ELGLHVQQNR 600
AILDHQQFDY IIRMMNCTLQ DCSSLEEYNI AAALLPLTSA FYRKLAPGVS QFAYTCVQDH 660
PIWTNQQFWE TTFYNAVQEQ VRSLYLSAKD DNHIPHLKQK LPDGQHQEKT AMDLAAEQLR 720
LWPTLSKSTQ QELVQHEEST VFSQAIHFAN LMVNLLVPLD TSKNKLLRAS APGDWESGSN 780
SIVTNSIAGS VAESYDTESG FEDSENSDVA NSVVRFIARF IDKVCTESGV TQDHIRSLHC 840
MIPGIVAMHI ETLEAVHRES RRLPPIQKPK ILRPALLPGE EIVCEGLRVL LDPDGREEAT 900
GGLLGGPQLL PAEGALFLTT YRILFRGTPH DQLVGEQTVV RSFPIASITK EKKITMQNQL 960
QQSVQEGLQI TSASFQLIKV AFDEEVSPEV VDIFKKQLMK FRYPQSIFST FAFAAGQTTP 1020
QIILPKQKEK NTSFRTFSKT IVKGAKKAGK MTIGRQYLLK KRTGTIVEER VNRPGWNEED 1080
DISVSDDSEL PTSTTLKASE KSTMEQLVEK ACFRDYQRLG LGTISGNSSR SKPEYFRVTA 1140
SNRLYSLCRS YPGLLVIPQA VQDSSLPRVA RCYRHNRLPV VCWKNSRSGT LLLRSGGFHG 1200
KGVVGLFKSQ NSPQAVSTSS LESSSSIEQE KYLQALLTAV IVHQKLRGSS TLTVRPALAL 1260
SPVHGYRDKS FTQSNPKSSA KEPVHNQGVW ASLRSSTRLI SSPTSFIDVG ARLAGKDHSA 1320
SFSNSTYLQN QLLKRQAALY IFGEKSQLRS SKVEFAFNCE FVPVEFHEIR QVKASFKKLM 1380
RACIPSTIPT DSEVTFLKAL GDSEWFPQLH RIMQLAVVVS EVLENGSSVW VCLEEGWDIT 1440
TQVTSLAQLL SDPFYRTIAG FRTLVEKEWL SFGHKFSQRS SLALNSQGGG FAPIFLQFLD 1500
CVHQVHNQYP TEFEFNLYYL KFLAFHYVSN RFKTFLLDSD YERLEHGTLF DDKGDKHAKK 1560
GVCIWECIDK MHTRSPIFFN YLYSPVEVEA LKPNVNVSSL KKWDYYTEET LSAGPSYDWM 1620
MLTPKHFPYE ESDVAGGAGP QSQRKTVWPC YDDVTCSQPD ALTRLFSEIE KLEHKLNQTP 1680
ERWHQLWEKV TTDLKEEPRT AHSLRHSAGS PGIASTNVPS YQKRPALHPL HRGLGEDQST 1740
TTAPSNGVEH RAATLYSQYT SKNDENRSFE GTLYKRGALL KGWKPRWFVL DVTKHQLRYY 1800
DSGEDTSCKG HIDLAEVEMV IPAGPSMGAP KYTSDKAFFD LKTSKRVYNF CAQDGQSAQQ 1860
WMDRIQSCIS DA 1872 
Gene Ontology
 GO:0005774; C:vacuolar membrane; IDA:MGI.
 GO:0016791; F:phosphatase activity; IEA:InterPro.
 GO:0019208; F:phosphatase regulator activity; IDA:MGI.
 GO:0035091; F:phosphatidylinositol binding; IDA:MGI.
 GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IEA:Compara.
 GO:0051262; P:protein tetramerization; IPI:MGI. 
Interpro
 IPR005112; dDENN_dom.
 IPR001194; DENN_dom.
 IPR004182; GRAM.
 IPR010569; Myotub-related.
 IPR017906; Myotubularin_phosphatase_dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR022096; SBF2.
 IPR005113; uDENN_dom. 
Pfam
 PF03455; dDENN
 PF02141; DENN
 PF02893; GRAM
 PF06602; Myotub-related
 PF00169; PH
 PF12335; SBF2
 PF03456; uDENN 
SMART
 SM00801; dDENN
 SM00799; DENN
 SM00568; GRAM
 SM00233; PH
 SM00800; uDENN 
PROSITE
 PS50947; DDENN
 PS50211; DENN
 PS50003; PH_DOMAIN
 PS51339; PPASE_MYOTUBULARIN
 PS50946; UDENN 
PRINTS