UniProt Accession

 GPP2_YEAST; P40106; D3DLW7 

Genbank Protein ID

 D50469; U18813; BK006939 

Genbank Nucleotide ID

 BAA09058.1; AAB64598.1; DAA07721.1 

Protein Name

 (DL)-glycerol-3-phosphatase 2 

Protein Synonyms/Alias

 Hyperosmolarity-responsive protein 2 

Gene Name

 HOR2 

Gene Synonyms/Alias

 GPP2; YER062C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
85	LEAEIPVKYGEKSIE	acetylation	[1]
89	IPVKYGEKSIEVPGA	acetylation	[1]
108	NALNALPKEKWAVAT	acetylation	[1]
110	LNALPKEKWAVATSG	acetylation	[1]
155	PHPEPYLKGRNGLGY	acetylation	[1]
173	EQDPSKSKVVVFEDA	ubiquitination	[2]
188	PAGIAAGKAAGCKII	ubiquitination	[2]
216	KGCDIIVKNHESIRV	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 DL-glycerol-3-phosphatase involved in glycerol biosynthesis. Plays a role in osmoadaptation. 

Sequence Annotation

 MOD_RES 90 90 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Phosphoprotein; Reference proteome; Stress response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 250 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000121; F:glycerol-1-phosphatase activity; IDA:SGD.
 GO:0006114; P:glycerol biosynthetic process; IMP:SGD.
 GO:0006970; P:response to osmotic stress; IDA:SGD. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006402; HAD-SF_hydro_IA_v3.
 IPR023198; PGP_dom2. 

Pfam

 PF13419; HAD_2 

SMART

  

PROSITE

  

PRINTS