| Tag | Content |
|---|
| CPLM ID | CPLM-019131 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Gamma-tubulin complex component 3 |
Protein Synonyms/Alias | GCP-3; hGCP3; Gamma-ring complex protein 104 kDa; h104p; hGrip104; Spindle pole body protein Spc98 homolog; hSpc98 |
Gene Name | TUBGCP3 |
Gene Synonyms/Alias | GCP3 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 220 | SSQATTSKGVPSAVS | ubiquitination | [1] | | 264 | VFQGIDGKNIKMNNT | ubiquitination | [1] | | 303 | ELGWLHNKIRRYTDQ | ubiquitination | [1] | | 551 | YLLDVLNKKYSLLDH | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 907 AA |
Protein Sequence | MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQYAVRVIG SNFAPTVERD EFLVAEKIKK 60
ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLSL SEDPRRQPSK VSSYATLFAQ 120
ALPRDAHSTP YYYARPQTLP LSYQDRSAQS AQSSGSVGSS GISSIGLCAL SGPAPAPQSL 180
LPGQSNQAPG VGDCLRQQLG SRLAWTLTAN QPSSQATTSK GVPSAVSRNM TRSRREGDTG 240
GTMEITEAAL VRDILYVFQG IDGKNIKMNN TENCYKVEGK ANLSRSLRDT AVRLSELGWL 300
HNKIRRYTDQ RSLDRSFGLV GQSFCAALHQ ELREYYRLLS VLHSQLQLED DQGVNLGLES 360
SLTLRRLLVW TYDPKIRLKT LAALVDHCQG RKGGELASAV HAYTKTGDPY MRSLVQHILS 420
LVSHPVLSFL YRWIYDGELE DTYHEFFVAS DPTVKTDRLW HDKYTLRKSM IPSFMTMDQS 480
RKVLLIGKSI NFLHQVCHDQ TPTTKMIAVT KSAESPQDAA DLFTDLENAF QGKIDAAYFE 540
TSKYLLDVLN KKYSLLDHMQ AMRRYLLLGQ GDFIRHLMDL LKPELVRPAT TLYQHNLTGI 600
LETAVRATNA QFDSPEILRR LDVRLLEVSP GDTGWDVFSL DYHVDGPIAT VFTRECMSHY 660
LRVFNFLWRA KRMEYILTDI RKGHMCNAKL LRNMPEFSGV LHQCHILASE MVHFIHQMQY 720
YITFEVLECS WDELWNKVQQ AQDLDHIIAA HEVFLDTIIS RCLLDSDSRA LLNQLRAVFD 780
QIIELQNAQD AIYRAALEEL QRRLQFEEKK KQREIEVEMC LYCV 824 |
Gene Ontology | GO:0005814; C:centriole; IDA:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO:0005827; C:polar microtubule; IDA:UniProtKB. GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB. GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB. GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. GO:0007020; P:microtubule nucleation; NAS:UniProtKB. GO:0007338; P:single fertilization; NAS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |