CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 TSC22 domain family protein 2 
Protein Synonyms/Alias
  
Gene Name
 TSC22D2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
122EQAMDLVKSHLMYAVubiquitination[1, 2, 3]
137REEVEVLKEQIKELVubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 204 AA 
Protein Sequence
XIQHVGLPLA PGTHSAPTSL PQSDLSQFQT QTQPLVGQVD DTRRKSEPLP QPPLSLIAEN 60
KPVVKPPVAD SLANPLQLTP MNSLATSVFS IAIPVDGDED SASGGGVVAI DNKIEQAMDL 120
VKSHLMYAVR EEVEVLKEQI KELVERNSLL ERENALLKSL SSNDQLSQLP TQQANPGSTS 180
QQQAVIAQPP QPTQPPQQPN VSSA 204 
Gene Ontology
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 
Interpro
 IPR000580; TSC-22_Dip_Bun. 
Pfam
 PF01166; TSC22 
SMART
  
PROSITE
 PS01289; TSC22 
PRINTS