CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003158
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anaerobic glycerol-3-phosphate dehydrogenase subunit A 
Protein Synonyms/Alias
 G-3-P dehydrogenase 
Gene Name
 glpA 
Gene Synonyms/Alias
 b2241; JW2235 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
142PALIGAVKVPDGTVDacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. 
Sequence Annotation
 NP_BIND 10 38 FAD (Potential).  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Direct protein sequencing; FAD; Flavoprotein; Membrane; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 542 AA 
Protein Sequence
MKTRDSQSSD VIIIGGGATG AGIARDCALR GLRVILVERH DIATGATGRN HGLLHSGARY 60
AVTDAESARE CISENQILKR IARHCVEPTN GLFITLPEDD LSFQATFIRA CEEAGISAEA 120
IDPQQARIIE PAVNPALIGA VKVPDGTVDP FRLTAANMLD AKEHGAVILT AHEVTGLIRE 180
GATVCGVRVR NHLTGETQAL HAPVVVNAAG IWGQHIAEYA DLRIRMFPAK GSLLIMDHRI 240
NQHVINRCRK PSDADILVPG DTISLIGTTS LRIDYNEIDD NRVTAEEVDI LLREGEKLAP 300
VMAKTRILRA YSGVRPLVAS DDDPSGRNVS RGIVLLDHAE RDGLDGFITI TGGKLMTYRL 360
MAEWATDAVC RKLGNTRPCT TADLALPGSQ EPAEVTLRKV ISLPAPLRGS AVYRHGDRTP 420
AWLSEGRLHR SLVCECEAVT AGEVQYAVEN LNVNSLLDLR RRTRVGMGTC QGELCACRAA 480
GLLQRFNVTT SAQSIEQLST FLNERWKGVQ PIAWGDALRE SEFTRWVYQG LCGLEKEQKD 540
AL 542 
Gene Ontology
 GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0010181; F:FMN binding; IEA:InterPro.
 GO:0052591; F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity; IEA:EC.
 GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro. 
Interpro
 IPR007419; BFD-like_2Fe2S-bd_dom.
 IPR006076; FAD-dep_OxRdtase.
 IPR000447; G3P_DH_FAD-dep.
 IPR017752; G3P_DH_GlpA_su. 
Pfam
 PF01266; DAO
 PF04324; Fer2_BFD 
SMART
  
PROSITE
 PS00977; FAD_G3PDH_1
 PS00978; FAD_G3PDH_2 
PRINTS
 PR01001; FADG3PDH.