CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019558
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DEP domain-containing protein 7 
Protein Synonyms/Alias
 Protein TR2/D15 
Gene Name
 DEPDC7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
225PLLDSLLKQQEAVPKubiquitination[1]
Reference
 [1] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572] 
Functional Description
  
Sequence Annotation
 DOMAIN 46 136 DEP.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 511 AA 
Protein Sequence
MATVQEKAAA LNLSALHSPA HRPPGFSVAQ KPFGATYVWS SIINTLQTQV EVKKRRHRLK 60
RHNDCFVGSE AVDVIFSHLI QNKYFGDVDI PRAKVVRVCQ ALMDYKVFEA VPTKVFGKDK 120
KPTFEDSSCS LYRFTTIPNQ DSQLGKENKL YSPARYADAL FKSSDIRSAS LEDLWENLSL 180
KPANSPHVNI SATLSPQVIN EVWQEETIGR LLQLVDLPLL DSLLKQQEAV PKIPQPKRQS 240
TMVNSSNYLD RGILKAYSDS QEDEWLSAAI DCLEYLPDQM VVEISRSFPE QPDRTDLVKE 300
LLFDAIGRYY SSREPLLNHL SDVHNGIAEL LVNGKTEIAL EATQLLLKLL DFQNREEFRR 360
LLYFMAVAAN PSEFKLQKES DNRMVVKRIF SKAIVDNKNL SKGKTDLLVL FLMDHQKDVF 420
KIPGTLHKIV SVKLMAIQNG RDPNRDAGYI YCQRIDQRDY SNNTEKTTKD ELLNLLKTLD 480
EDSKLSAKEK KKLLGQFYKC HPDIFIEHFG D 511 
Gene Ontology
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
 GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. 
Interpro
 IPR000591; DEP_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP 
SMART
 SM00049; DEP 
PROSITE
 PS50186; DEP 
PRINTS