CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007137
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosomal RNA small subunit methyltransferase C 
Protein Synonyms/Alias
 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase RsmC 
Gene Name
 rsmC 
Gene Synonyms/Alias
 yjjT; b4371; JW4333 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
133ADYAPLNKVDSARRCacetylation[1]
149LYFGRLEKQPVFDAEacetylation[1]
157QPVFDAEKFWGEYSVacetylation[1]
197STLTPHTKGKVLDVGacetylation[1]
259SNVFSEVKGRFDMIIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Magnesium; Methyltransferase; Reference proteome; rRNA processing; S-adenosyl-L-methionine; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARLDTA ASRAHTQQFH HWQVLSRQMG 60
DNARFSLVAT ADDVADCDTL IYYWPKNKPE AQFQLMNLLS LLPVGTDIFV VGENRSGVRS 120
AEQMLADYAP LNKVDSARRC GLYFGRLEKQ PVFDAEKFWG EYSVDGLTVK TLPGVFSRDG 180
LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SVAFARHSPK IRLTLCDVSA PAVEASRATL 240
AANGVEGEVF ASNVFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR 300
IVANAFLPYP DVLDETFGFH EVIAQTGRFK VYRAIMTRQA KKG 343 
Gene Ontology
 GO:0005737; C:cytoplasm; IC:UniProtKB.
 GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IDA:EcoCyc.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0070475; P:rRNA base methylation; IMP:EcoCyc. 
Interpro
 IPR002052; DNA_methylase_N6_adenine_CS.
 IPR013675; Mtase_sm_N.
 IPR023543; rRNA_ssu_MeTfrase_C.
 IPR007848; Small_mtfrase_dom. 
Pfam
 PF05175; MTS
 PF08468; MTS_N 
SMART
  
PROSITE
  
PRINTS