UniProt Accession

 H7BZ20_HUMAN; H7BZ20 

Genbank Protein ID

 AC133528 

Genbank Nucleotide ID

  

Protein Name

 Thymidylate kinase 

Protein Synonyms/Alias

  

Gene Name

 DTYMK 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
165	RCFHQLMKDTTLNWK	acetylation	[1]
178	WKMVDASKSIEAVHE	ubiquitination	[2]

Reference

 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 192 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004798; F:thymidylate kinase activity; IEA:InterPro.
 GO:0006233; P:dTDP biosynthetic process; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR018095; Thymidylate_kin_CS.
 IPR018094; Thymidylate_kinase. 

Pfam

  

SMART

  

PROSITE

 PS01331; THYMIDYLATE_KINASE 

PRINTS