CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014106
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Scm-like with four MBT domains protein 2 
Protein Synonyms/Alias
  
Gene Name
 SFMBT2 
Gene Synonyms/Alias
 KIAA1617 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
150PPDAIKEKYTDWTEFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 REPEAT 44 144 MBT 1.
 REPEAT 152 256 MBT 2.
 REPEAT 266 372 MBT 3.
 REPEAT 380 477 MBT 4.
 DOMAIN 824 887 SAM.  
Keyword
 3D-structure; Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 894 AA 
Protein Sequence
MESTLSASNM QDPSSSPLEK CLGSANGNGD LDSEEGSSLE ETGFNWGEYL EETGASAAPH 60
TSFKHVEISI QSNFQPGMKL EVANKNNPDT YWVATIITTC GQLLLLRYCG YGEDRRADFW 120
CDVVIADLHP VGWCTQNNKV LMPPDAIKEK YTDWTEFLIR DLTGSRTAPA NLLEGPLRGK 180
GPIDLITVGS LIELQDSQNP FQYWIVSVIE NVGGRLRLRY VGLEDTESYD QWLFYLDYRL 240
RPVGWCQENK YRMDPPSEIY PLKMASEWKC TLEKSLIDAA KFPLPMEVFK DHADLRSHFF 300
TVGMKLETVN MCEPFYISPA SVTKVFNNHF FQVTIDDLRP EPSKLSMLCH ADSLGILPVQ 360
WCLKNGVSLT PPKGYSGQDF DWADYHKQHG AQEAPPFCFR NTSFSRGFTK NMKLEAVNPR 420
NPGELCVASV VSVKGRLMWL HLEGLQTPVP EVIVDVESMD IFPVGWCEAN SYPLTAPHKT 480
VSQKKRKIAV VQPEKQLPPT VPVKKIPHDL CLFPHLDTTG TVNGKYCCPQ LFINHRCFSG 540
PYLNKGRIAE LPQSVGPGKC VLVLKEVLSM IINAAYKPGR VLRELQLVED PHWNFQEETL 600
KAKYRGKTYR AVVKIVRTSD QVANFCRRVC AKLECCPNLF SPVLISENCP ENCSIHTKTK 660
YTYYYGKRKK ISKPPIGESN PDSGHPKPAR RRKRRKSIFV QKKRRSSAVD FTAGSGEESE 720
EEDADAMDDD TASEETGSEL RDDQTDTSSA EVPSARPRRA VTLRSGSEPV RRPPPERTRR 780
GRGAPAASSA EEGEKCPPTK PEGTEDTKQE EEERLVLESN PLEWTVTDVV RFIKLTDCAP 840
LAKIFQEQDI DGQALLLLTL PTVQECMELK LGPAIKLCHQ IERVKVAFYA QYAN 894 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR021987; DUF3588.
 IPR004092; Mbt.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1. 
Pfam
 PF12140; DUF3588
 PF02820; MBT
 PF00536; SAM_1 
SMART
 SM00561; MBT
 SM00454; SAM 
PROSITE
 PS51079; MBT
 PS50105; SAM_DOMAIN 
PRINTS