CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018246
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable palmitoyltransferase ZDHHC1 
Protein Synonyms/Alias
 DHHC domain-containing cysteine-rich protein 1; Zinc finger DHHC domain-containing protein 1; DHHC-1; Zinc finger protein 377 
Gene Name
 ZDHHC1 
Gene Synonyms/Alias
 C16orf1; ZNF377 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18SNKTAPEKSVWTAPAubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 ZN_FING 134 184 DHHC-type.  
Keyword
 Acyltransferase; Complete proteome; Membrane; Metal-binding; Polymorphism; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MYKMNICNKP SNKTAPEKSV WTAPAQPSGP SPELQGQRSR RNGWSWPPHP LQIVAWLLYL 60
FFAVIGFGIL VPLLPHHWVP AGYACMGAIF AGHLVVHLTA VSIDPADANV RDKSYAGPLP 120
IFNRSQHAHV IEDLHCNLCN VDVSARSKHC SACNKCVCGF DHHCKWLNNC VGERNYRLFL 180
HSVASALLGV LLLVLVATYV FVEFFVNPMR LRTNRHFEVL KNHTDVWFVF LPAAPVETQA 240
PAILALAALL ILLGLLSTAL LGHLLCFHIY LMWHKLTTYE YIVQHRPPQE AKGVHRELES 300
CPPKMRPIQE MEFYMRTFRH MRPEPPGQAG PAAVNAKHSR PASPDPTPGR RDCAGPPVQV 360
EWDRKKPLPW RSPLLLLAMW GPQAPPCLCR KRGRGACIKC ERLRPRIRRR GLGPPAAAPA 420
RRRIPRTPAL CTPLALPAPT TRRRQSPWTR FQWRRRAWAA PLWPPRGAGA DSPRWRGRRV 480
RPPFS 485 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; NAS:UniProtKB.
 GO:0016409; F:palmitoyltransferase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0018345; P:protein palmitoylation; IEA:Compara. 
Interpro
 IPR001594; Znf_DHHC_palmitoyltrfase. 
Pfam
 PF01529; zf-DHHC 
SMART
  
PROSITE
 PS50216; ZF_DHHC 
PRINTS