CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034237
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG18410, isoform CRA_a 
Protein Synonyms/Alias
 Protein Ddx23 
Gene Name
 Ddx23 
Gene Synonyms/Alias
 mCG_18410 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
149SLEELLAKKKAEEEAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 819 AA 
Protein Sequence
MAGELADKKD RDASPKEERK RSRTPERDRD RDRDRKSSPS KDRKRHRSRD RRRGGSRSRS 60
RSRSKSVERE RRHKERERDK ERDRSKKERE RDKDGHRRDK DRKRSSLSPG RGKDFKSRKD 120
RDSKKGDEDE HGDKRPKIQP LSLEELLAKK KAEEEAEAKP KFLSKAEREA EALKRRQQEV 180
EERQKMLEEE RKKRKQFQDL GRKMLEDPQE RERRERRERM ERETNGNEDE EGRQKIREEK 240
DKSKELHAIK ERYLGGIKKR RRTRHLNDRK FVFEWDASED TSIDYNPLYK ERHQVQLLGR 300
GFIAGIDLKQ QKREQSRFYG DLMEKRRTLE EKEQEEARLR KLRKKEAKQR WDDRHWSQKK 360
LDEMTDRDWR IFREDYSITT KGGKIPNPIR SWKDSSLPPH ILEVIDKCGY KEPTPIQRQA 420
IPIGLQNRDI IGVAETGSGK TAAFLIPLLV WITTLPKIDR IEESDQGPYA IILAPTRELA 480
QQIEEETIKF GKPLGIRTVA VIGGISREDQ GFRLRMGCEI VIATPGRLID VLENRYLVLS 540
RCTYVVLDEA DRMIDMGFEP DVQKILEHMP VSNQKPDTDE AEDPEKMLAN FESGKHKYRQ 600
TVMFTATMPP AVERLARSYL RRPAVVYIGS AGKPHERVEQ KVFLMSESEK RKKLLAILEQ 660
GFDPPIIIFV NQKKGCDVLA KSLEKMGYNA CTLHGGKGQE QREFALSNLK AGAKDILVAT 720
DVAGRGIDIQ DVSMVVNYDM AKNIEDYIHR IGRTGRAGKS GVAITFLTKE DSAVFYELKQ 780
AILESPVSSC PPELANHPDA QHKPGTILTK KRREETIFA 819 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005682; C:U5 snRNP; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000629; RNA-helicase_DEAD-box_CS.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS00039; DEAD_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS