CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012864
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable proline dehydrogenase 2 
Protein Synonyms/Alias
 Probable proline oxidase 2; Proline oxidase-like protein 
Gene Name
 Prodh2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
32DGGAFHLKRTAELARacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Converts proline to delta-1-pyrroline-5-carboxylate (Probable). 
Sequence Annotation
  
Keyword
 Complete proteome; FAD; Flavoprotein; Oxidoreductase; Proline metabolism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 456 AA 
Protein Sequence
MIWTRLPLYG HSKPSTGGWQ PLRFDGGAFH LKRTAELARA LLVLRLCAWP PLVTHGLAFQ 60
AWSQRLLGSR LSGALLRASI YGQFVAGETA EEVRGCVQQL QAIGLQPLLA VPTEEEPDSA 120
AKTSEAWYEG NLSAMLHCVD LSRAVADAHG PARNSLMQLK VTALTSPRLC KELSAWIQRP 180
RGSSELRPER LAEAMESGRN LQLSCLSTEQ NQHLQASLSR LHRVAQHARA QDVRLLVDAE 240
YTFINPALSL LVAALAMRLD SSEEEGPWVW NTYQAYLKDT HERLERDAKA AHEAGLAFGV 300
KLVRGAYLDK ERSVTQLHGK EDCTQPDYEA TSRSYSRCLE LMLRRVSNHG PRCHLMVASH 360
NEESIRQATR RMWELGIPLD GPVCFGQLLG MCDHVSLALG QAGYMVYKSI PYGCLEEVIP 420
YLIRRAQENR SVLQGARREQ ALLSQELWRR LLGRTA 456 
Gene Ontology
 GO:0004657; F:proline dehydrogenase activity; IEA:EC.
 GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
 GO:0010133; P:proline catabolic process to glutamate; IEA:UniProtKB-UniPathway. 
Interpro
 IPR002872; Proline_DH.
 IPR015659; Proline_oxidase. 
Pfam
 PF01619; Pro_dh 
SMART
  
PROSITE
  
PRINTS