CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038666
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Signal transducer and activator of transcription 2 
Protein Synonyms/Alias
  
Gene Name
 Stat2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
238LPKLDEWKVQQQKSCubiquitination[1]
289MSHMLRYKGDMFGQGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 923 AA 
Protein Sequence
MAQWEMLQNL DSLFLDQLHQ VYSQSILPMD VRQHLATWIE DQNWREAALG SDDAKANMLY 60
FSILDQLNQW DHYSSDSNHF LLQHNLRKFS RDIQTFPNGP TQLAEMIFNL LLEEQRILNQ 120
AQRAQEVQPP PAPEAVVESQ QLEIENRIQG LHVDIEFLVR SIRQLKDEQD VFSFRYTVFS 180
LKKTSSSDPH QSQQAQLVQA TANKVDRMRK EVLDISKGLV GRLTTLVDLL LPKLDEWKVQ 240
QQKSCIGAPP PELQLEQLEQ WLTAGAKFLF HLRQLLKQLK EMSHMLRYKG DMFGQGVDLQ 300
NAQVMELLQR LLQRSFVVET QPCMPQTLHR PLILKTGNKF TVRTRLLVRL QEGSESLKAE 360
VSVDRNSDLP GFRKFNILTS NQKTLTPEEG QRQGLIWDFG FLTLVEQRAV GAGKGNKQGP 420
LAVTEELHVI SFVVEYVYQG LKMKLQTDTL PVVIISNMNQ LSIAWASILW FNMLSPNPKN 480
QQFFCQAPKA PWSLLGPVLS WQFSSYVGRG LDSEQLGMLR TKLFGKSCKM EDALLSWVDF 540
CKRESPPGKI PFWTWLDKIL ELVHDHLKDL WKDGRIMGFV SRNQERRLLK KMLSGTFLLR 600
FSETSEGGIT CSWVEHQDDD KVEIYSVQPY TKEVLQSLPL TEIIRHYQVL AEENIPENPL 660
RFLYPRIPRD EAFGCYYQEK VNFEEQRKYL KHKLIVISNR QVDELQQPLE LKQDSESLEV 720
NAELLLAHDQ ELPLMMQTGL VLGTELKVDP ILSTAPQVLL EPAPQVLLEP APQVPLEPAP 780
QVLLEPAPQV LLEPAPQVLL EPAPQVLLEP APQVQLEPAP QVLLELAPQV LLEPAPQVLL 840
ELAPQVQLEP AHLLQQPSES DLPEDLQQIS VEDLKKLSNP STEYITTNEN PMLAGESSGD 900
ETSIPYHSHF DADGLLGWTL DTF 923 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR008967; p53-like_TF_DNA-bd.
 IPR000980; SH2.
 IPR022756; STAT2_C.
 IPR013800; STAT_TF_alpha.
 IPR015988; STAT_TF_coiled-coil.
 IPR001217; STAT_TF_core.
 IPR013801; STAT_TF_DNA-bd.
 IPR012345; STAT_TF_DNA-bd_sub.
 IPR013799; STAT_TF_prot_interaction. 
Pfam
 PF00017; SH2
 PF12188; STAT2_C
 PF01017; STAT_alpha
 PF02864; STAT_bind
 PF02865; STAT_int 
SMART
 SM00252; SH2
 SM00964; STAT_int 
PROSITE
 PS50001; SH2 
PRINTS