Tag | Content |
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CPLM ID | CPLM-005783 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP synthase subunit epsilon, mitochondrial |
Protein Synonyms/Alias | ATPase subunit epsilon |
Gene Name | Atp5e |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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37 | EFKANAEKTSGTSIK | acetylation | [1] | 44 | KTSGTSIKTVKIKKE | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
Sequence Annotation | MOD_RES 21 21 N6-acetyllysine (By similarity). |
Keyword | Acetylation; ATP synthesis; CF(1); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 51 AA |
Protein Sequence | MVAYWRQAGL SYIRFSQICA KAVRDALKTE FKANAEKTSG TSIKTVKIKK E 51 |
Gene Ontology | GO:0000275; C:mitochondrial proton-transporting ATP synthase complex, catalytic core F(1); IDA:RGD. GO:0016887; F:ATPase activity; IMP:RGD. GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro. GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro. GO:0006172; P:ADP biosynthetic process; IDA:RGD. GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. |
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