CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036159
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 F-actin-capping protein subunit alpha-2 
Protein Synonyms/Alias
  
Gene Name
 Capza2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
86HGDLGNGKFLDPKNRacetylation[1, 2, 3]
86HGDLGNGKFLDPKNRubiquitination[4]
97PKNRICFKFDHLRKEacetylation[1]
133TALRAYVKEHYPNGVubiquitination[4]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 174 AA 
Protein Sequence
MADLEEQLSD EEKVRIAAKF IIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNLD 60
QFTPVKIEGY EDQVLITEHG DLGNGKFLDP KNRICFKFDH LRKEATDPRP YEAENAIESW 120
RTSVETALRA YVKEHYPNGV CTVYGKKVDG QQTIIACIES HQFQAKNFCC CFYF 174 
Gene Ontology
 GO:0030863; C:cortical cytoskeleton; IDA:MGI.
 GO:0008290; C:F-actin capping protein complex; IPI:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR002189; WASH_F-actin_cap_alpha. 
Pfam
 PF01267; F-actin_cap_A 
SMART
  
PROSITE
  
PRINTS