CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015332
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 OGFOD3 
Gene Synonyms/Alias
 C17orf101 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
168LYRYFGDKIQNIFSEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 DOMAIN 207 309 Fe2OG dioxygenase.
 ACT_SITE 298 298 Potential.
 METAL 230 230 Iron (By similarity).
 METAL 232 232 Iron (By similarity).
 METAL 288 288 Iron (By similarity).
 BINDING 298 298 2-oxoglutarate (Potential).
 CARBOHYD 215 215 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Dioxygenase; Glycoprotein; Iron; Membrane; Metal-binding; Oxidoreductase; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix; Vitamin C. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 319 AA 
Protein Sequence
MAPQRRAATK APEGNGAAER RNRSSTKKDR APREVQRLWQ RPWLRTAGLG AGFVLTALLL 60
WSSLGADDGV AEVLARRGEV VAGRFIEVPC SEDYDSHRRF EGCTPRKCGR GVTDVVITRE 120
EAERIRSVAE KGLSLGGSDG GASILDLHSG ALSVGKHFVN LYRYFGDKIQ NIFSEEDFRL 180
YREVRQKVQL TIAEAFGISA SSLHLTKPTF FSRINSTEAR TAHDEYWHAH VDKVTYGSFD 240
YTSLLYLSNY LEDFGGGRFM FMEEGANKTV EPRAGRVSFF TSGSENLHRV EKVHWGTRYA 300
ITIAFSCNPD HGIEDPAFP 319 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
 GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
 GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. 
Interpro
 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph. 
Pfam
 PF13640; 2OG-FeII_Oxy_3 
SMART
 SM00702; P4Hc 
PROSITE
 PS51471; FE2OG_OXY 
PRINTS