CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035920
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 SH3 domain-binding protein 2 
Protein Synonyms/Alias
  
Gene Name
 SH3BP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
86TMPGGVAKAGYLHKKubiquitination[1]
487FRSFSFEKPRQPSQAubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 618 AA 
Protein Sequence
MAGSGPRPRS WGRREAGARD EAAAAGGRGP GPCRCSQGRR AWIAPGKPAM PAAWTPFMAA 60
EEMHWPVPMK AIGAQNLLTM PGGVAKAGYL HKKGGTQLQL LKWPLRFVII HKRCVYYFKS 120
STSASPQGAF SLSGYNRVMR AAEETTSNNV FPFKIIHISK KHRTWFFSAS SEEERKSWMA 180
LLRREIGHFH EKKDLPLDTS DSSSDTDSFY GAVERPVDIS LSPYPTDNED YEHDDEDDSY 240
LEPDSPEPGR LEDALMHPPA YPPPPVPTPR KPAFSDMPRA HSFTSKGPGP LLPPPPPKHG 300
LPDVGLAAED SKRDPLCPRR AEPCPRVPAT PRRMSDPPLS TMPTAPGLRK PPCFRESASP 360
SPEPWTPGHG ACSTSSAAIM ATATSRNCDK LKSFHLSPRG PPTSEPPPVP ANKPKFLKIA 420
EEDPPREAAM PGLFVPPVAP RPPALKLPVP EAMARPAVLP RPEKPQLPHL QRSPPDGQSF 480
RSFSFEKPRQ PSQADTGGDD SDEDYEKVPL PNSVFVNTTE SCEVERLFKA TSPRGEPQDG 540
LYCIRNSSTK SGKVLVVWDE TSNKVRNYRI FEKDSKFYLE GEVLFVSVGS MVEHYHTHVL 600
PSHQSLLLRH PYGYTGPR 618 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000980; SH2. 
Pfam
 PF00169; PH
 PF00017; SH2 
SMART
 SM00233; PH
 SM00252; SH2 
PROSITE
 PS50003; PH_DOMAIN
 PS50001; SH2 
PRINTS