CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Conserved oligomeric Golgi complex subunit 1 
Protein Synonyms/Alias
  
Gene Name
 COG1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11AATSPALKRLDLRDPubiquitination[1, 2]
45RAEIEHKKEELRQMVubiquitination[2]
81VGLVDAVKATDQYCAubiquitination[2]
377LMYVKSMKGLAGIRDmethylation[3]
431DRLQTLTKEGFDSISubiquitination[4, 5]
524FCSALDSKLKVKLDDubiquitination[2]
526SALDSKLKVKLDDLLubiquitination[2]
553DVSPTQAKSSAFDRYubiquitination[4]
607QDALNSAKLHSVLFMubiquitination[2]
666EIIPTQAKWQEVKEVubiquitination[4]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [5] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 962 AA 
Protein Sequence
XATAATSPAL KRLDLRDPAA LFETHGAEEI RGLERQVRAE IEHKKEELRQ MVGERYRDLI 60
EAADTIGQMR RCAVGLVDAV KATDQYCARL RQAGSAAPRP PRAQQPQQPS QEKFYSMAAQ 120
IKLLLEIPEK IWSSMEASQC LHATQLYLLC CHLHSLLQLD SSSSRYSPVL SRFPILIRQV 180
AAASHFRSTI LHESKMLLKC QGVSDQAVAE ALCSIMLLEE SSPRQALTDF LLARKATIQK 240
LLNQPHHGAG IKAQICSLVE LLATTLKQAH ALFYTLPEGL LPDPALPCGL LFSTLETITG 300
QHPAGKGTGV LQEEMKLCSW FKHLPASIVE FQPTLRTLAH PISQEYLKDT LQKWIHMCNE 360
DIKNGITNLL MYVKSMKGLA GIRDAMWELL TNESTNHSWD VLCRRLLEKP LLFWEDMMQQ 420
LFLDRLQTLT KEGFDSISSS SKELLVSALQ ELESSTSNSP SNKHIHFEYN MSLFLWSESP 480
NDLPSDAAWV SVANRGQFAS SGLSMKAQAI SPCVQNFCSA LDSKLKVKLD DLLAYLPSDD 540
SSLPKDVSPT QAKSSAFDRY ADAGTVQEML RTQSVACIKH IVDCIRAELQ SIEEGVQGQQ 600
DALNSAKLHS VLFMARLCQS LGELCPHLKQ CILGKSESSE KPAREFRALR KQGKVKTQEI 660
IPTQAKWQEV KEVLLQQSVM GYQVWSSAVV KVLIHGFTQS LLLDDAGSVL ATATSWDELE 720
IQEEAESGSS VTSKIRLPAQ PSWYVQSFLF SLCQEINRVG GHALPKVTLQ EMLKSCMVQV 780
VAAYEKLSEE KQIKKEGAFP VTQNRALQLL YDLRYLNIVL TAKGDEVKSG RSKPDSRIEK 840
VTDHLEALID PFDLDVFTPH LNSNLHRLVQ RTSVLFGLVT GTENQLAPRS STFNSQEPHN 900
ILPLASSQIR FGLLPLSMTS TRKAKSTRNI ETKAQVGAKS KRLIRGWVPT SHRATHDQLP 960
FK 962 
Gene Ontology
  
Interpro
 IPR014812; Vps51. 
Pfam
 PF08700; Vps51 
SMART
  
PROSITE
  
PRINTS