UniProt Accession

 YFBT_ECOLI; P77625 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC75353.2; BAA16129.2 

Protein Name

 Sugar phosphatase YfbT 

Protein Synonyms/Alias

  

Gene Name

 yfbT 

Gene Synonyms/Alias

 b2293; JW5376 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
46	VLAFIHGKQAITSLR	acetylation	[1]
59	LRHFMAGKSEADIAA	acetylation	[1]
118	PVARARHKIAGLPAP	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the dephosphorylation of different sugar phosphates including ribose-5-phosphate (Ribu5P), fructose-1- phosphate (Fru1P), fructose-6-phosphate (Fru6P), glucose-6- phosphate (Glu6P). Selectively hydrolyzes beta-D-glucose-1- phosphate (bGlu1P) and has no activity with the alpha form. 

Sequence Annotation

 REGION 9 11 Substrate (By similarity).
 ACT_SITE 9 9 Nucleophile (By similarity).
 METAL 9 9 Magnesium (By similarity).
 METAL 11 11 Magnesium (By similarity).
 METAL 163 163 Magnesium (By similarity).  

Keyword

 Cobalt; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0050897; F:cobalt ion binding; IDA:UniProtKB.
 GO:0043136; F:glycerol-3-phosphatase activity; IDA:EcoCyc.
 GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
 GO:0030145; F:manganese ion binding; IDA:UniProtKB.
 GO:0008967; F:phosphoglycolate phosphatase activity; IEA:InterPro.
 GO:0050308; F:sugar-phosphatase activity; IDA:UniProtKB. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006439; HAD-SF_hydro_IA_v1.
 IPR006402; HAD-SF_hydro_IA_v3.
 IPR005833; Haloacid_DH/epoxide_hydro.
 IPR023198; PGP_dom2. 

Pfam

 PF00702; Hydrolase 

SMART

  

PROSITE

  

PRINTS

 PR00413; HADHALOGNASE.