CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027103
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ac1002 
Protein Synonyms/Alias
  
Gene Name
 Adh4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
454HLLPPPRKPAYIKPRacetylation[1]
459PRKPAYIKPRLRRSAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Oxidoreductase; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 872 AA 
Protein Sequence
MCDSGELWPM TPVLRPHVAQ VITCKAAIAW KTDSPLCIEE IEVSPPKAHE VRIKVIATCV 60
CPTDINATNP KKKALFPVVL GHECAGIVES VGPGVTNFKP GDKVIPFFAP QCKKCKLCLS 120
PLTNLCGKLR NFKYPTIDQE LMEDRTSRFT CKGRSIYHFM GVSSFSQYTV VSEANLARVD 180
DEANLERVCL IGCGFTSGYG AAINTAKVTP GSACAVFGLG CVGLSAVIGC KIAGASRIIA 240
IDINSEKFPK AKALGATDCL NPRDLDKPVQ DVITELTGGG VDFSLDCAGT AQTLGRAQER 300
QDPCLRHRRN LKETDRINSS LHPNPVGGRA EPSERQTRLG NQKRLQSVHI QTPEENTKRH 360
LEPWCTEAPG KSGADLPGCC RRGEDLGSTP RANLSLGTTG WKSVDSVPNL VTDYKNKKFD 420
LDLLVTHALP FDKINDAIDL MNQGKRHLLP PPRKPAYIKP RLRRSAPPLT HAGLIPGFRY 480
TFVPLRSLDP ELADMANQVI RCKAAVAWEA GKPLSIEEIE VAPPQAHEVR IKIIATAVCH 540
TDAYTLSGAD PEGCFPVILG HEGAGIVESV GEGVTKLKAG DTVIPLYIPQ CGECKFCLNP 600
KTNLCQKIRV TQGKGLMPDG TSRFTCKGKP ILHFMGTSTF SEYTVVADIS VAKIDPSAPL 660
DKVCLLGCGI STGYGAAVNT AKVEPGSTCA VFGLGGVGLA VIMGCKVAGA SRIIGIDINK 720
DKFAKAKEFG ATECINPQDF SKSIQEVLIE MTDGGVDFSF ECIGNVKVMK PLSMPWPESQ 780
RSALEAAHKG WGVSVVVGVA ASGEEISTRP FQLVTGRTWK GTAFGGWKSV ESVPKLVSEY 840
MSKKIKVDEF VTGNLSFDQI NKAFDLMHSG NR 872 
Gene Ontology
 GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006069; P:ethanol oxidation; IEA:InterPro. 
Interpro
 IPR014183; ADH_3.
 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF08240; ADH_N
 PF00107; ADH_zinc_N 
SMART
  
PROSITE
 PS00059; ADH_ZINC 
PRINTS