Tag | Content |
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CPLM ID | CPLM-023350 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acidic leucine-rich nuclear phosphoprotein 32 family member A |
Protein Synonyms/Alias | |
Gene Name | Anp32a |
Gene Synonyms/Alias | Mapmodulin; CG5784 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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102 | IKDLETLKPLEEFKN | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex (By similarity). |
Sequence Annotation | REPEAT 16 37 LRR 1. REPEAT 39 60 LRR 2. REPEAT 61 83 LRR 3. REPEAT 84 105 LRR 4. DOMAIN 118 156 LRRCT. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Leucine-rich repeat; Nucleus; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 261 AA |
Protein Sequence | MEKRIELERR ARKVNQITEL NLDNCRSTSI VGLTDEYTAL ESLSLINVGL TTLKGFPKLP 60 NLKKLELSDN RISSGLNYLT TSPKLQYLNL SGNKIKDLET LKPLEEFKNL VVLDLFNNDA 120 TQVDNYREKI FKMLPSLNFL DGFDCNDEEV QSDGDDDDEV NGNDSDEVGV SDEDDDSDDS 180 DEEANGEVSL SEVYNDDLEE DNSDWEGEDE AGEEDEEEDS DIDDADGDAN ESAASVNAKD 240 KDGEKEADES QVRGKKRKHD G 261 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB. GO:0005875; C:microtubule associated complex; ISS:FlyBase. GO:0005634; C:nucleus; ISS:UniProtKB. GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. GO:0008017; F:microtubule binding; ISS:FlyBase. GO:0007017; P:microtubule-based process; ISS:FlyBase. GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB. |
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