| Tag | Content |
|---|
| CPLM ID | CPLM-013773 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase TRIM41 |
Protein Synonyms/Alias | Tripartite motif-containing protein 41 |
Gene Name | Trim41 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 307 | TELKSQMKSELAAVA | ubiquitination | [1] | | 575 | TLLSPCEKPRRFGVY | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C (By similarity). |
Sequence Annotation | DOMAIN 413 630 B30.2/SPRY.
ZN_FING 20 61 RING-type; degenerate.
ZN_FING 222 263 B box-type.
MOD_RES 447 447 Phosphoserine (By similarity). |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Ligase; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 630 AA |
Protein Sequence | MAAVAMTPNP VQTLQEEAVC AICLDYFTDP VSIGCGHNFC RVCVTQLWGG EDEEDRDELD 60
REEEEEEVGE EEEVEAVGAG GGWDTPMREE DYEGDMEEEA EEEEEVFWSS GIGGSNWDNM 120
DYVWEEEEEE EEEELDYYLG DVADLRGEDE DEEEEVLEED EEEELDPITQ LPPPPAPRRC 180
FTCPQCRKSF PRRSFRPNLQ LANMVQVIRQ MHPTPGRGSR VNEQGICPRH QEALKLFCEV 240
DEEAICVVCR ESRSHKQHSV VPLEEVVQEY KAKLQGHVEP LRKHLEAVQK MKAKEERRVT 300
ELKSQMKSEL AAVASEFGRL TRFLAEEQAG LERRLREMHE AQLGRAGAAA NRLEEQAAQL 360
SRLLAEAQER SQQGGLRLLQ DIKETFNRCE EIQLQPPEIW SPDPCQPHSH DFLTDAIVRK 420
MSRMFCQAAR VDLTLDPDTA HPALLLSPDR RGVRLAERRQ EVPEHSKRFS ADCCVLGAQG 480
FRSGRHYWEV EVGGRRGWAV GAARESTHHK EKVGSGGSSV SSGDASSSRH HHRRRRLHLP 540
QQLLLQREVW CVGTHGKRYQ AQSSTEQTLL SPCEKPRRFG VYLDYEAGRL GFYNADTLAH 600
VHTFSAAFLG ERVFPFFRVL SKGTRIKLCP 630 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0016874; F:ligase activity; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |