CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031713
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein NLRC3 
Protein Synonyms/Alias
  
Gene Name
 NLRC3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
73HRKALLSKVGGGPELubiquitination[1]
187RDLNTHEKLCADRLIubiquitination[1, 2]
241VACTDPKKEIPVDHLubiquitination[1]
379LSGEGQEKGKASPRIubiquitination[1]
381GEGQEKGKASPRIEQubiquitination[1]
410LAFHGLLKKKYVFYEubiquitination[1]
670GKDCRIQKISLAENQubiquitination[1, 3]
681AENQISNKGAKALARubiquitination[1, 2]
759LSMLHLQKNSIGPMGubiquitination[1]
780LKQNRSLKELMFSSNubiquitination[1]
1026RMISEAIKTNAPTCTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1036 AA 
Protein Sequence
MRKQEVRTGR EAGQGHGTGS PAEQVKALMD LLAGKGSQGS QAPQALDRTP DAPLGPCSND 60
SRIQRHRKAL LSKVGGGPEL GGPWHRLASL LLVEGLTDLQ LREHDFTQVE ATRGGGHPAR 120
TVALDRLFLP LSRVSVPPRV SITIGVAGMG KTTLVRHFVR LWAHGQVGKD FSLVLPLTFR 180
DLNTHEKLCA DRLICSVFPH VGEPSLAVAV PARALLILDG LDECRTPLDF SNTVACTDPK 240
KEIPVDHLIT NIIRGNLFPE VSIWITSRPS ASGQIPGGLV DRMTEIRGFN EEEIKVCLEQ 300
MFPEDQALLG WMLSQVQADR ALYLMCTVPA FCRLTGMALG HLWRSRTGPQ DAELWPPRTL 360
CELYSWYFRM ALSGEGQEKG KASPRIEQVA HGGRKMVGTL GRLAFHGLLK KKYVFYEQDM 420
KAFGVDLALL QGAPCSCFLQ REETLASSVA YCFTHLSLQE FVAAAYYYGA SRRAIFDLFT 480
ESGVSWPRLG FLTHFRSAAQ RAMQAEDGRL DVFLRFLSGL LSPRVNALLA GSLLAQGEHQ 540
AYRTQVAELL QGCLRPDAAV CARAINVLHC LHELQHTELA RSVEEAMESG ALARLTGPAH 600
RAALAYLLQV SDACAQEANL SLSLSQGVLQ SLLPQLLYCR KLRLDTNQFQ DPVMELLGSV 660
LSGKDCRIQK ISLAENQISN KGAKALARSL LVNRSLTSLD LRGNSIGPQG AKALADALKI 720
NRTLTSLSLQ GNTVRDDGAR SMAEALASNR TLSMLHLQKN SIGPMGAQRM ADLKQNRSLK 780
ELMFSSNSIG DGGAKALAEA LKVNQGLESL DLQSNSISDA GVAALMGALC TNQTLLSLSL 840
RENSISPEGA QAIAHALCAN STLKNLDLQW NFIQAGAAQA LGQALQLNRS LTSLDLQENA 900
IGDDGACAVA RALKVNTALT ALYLQVASIG ASGAQVLGEA LAVNRTLEIL DLRGNAIGVA 960
GAKALANALK VNSSLRRLNL QENSLGMDGA ICIATALSGN HRLQHINLQG NHIGDSGARM 1020
ISEAIKTNAP TCTVEM 1036 
Gene Ontology
  
Interpro
 IPR007111; NACHT_NTPase. 
Pfam
  
SMART
  
PROSITE
 PS50837; NACHT 
PRINTS