CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038940
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Gap junction protein 
Protein Synonyms/Alias
  
Gene Name
 Gjc3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
255DLSVVETKEPF****ubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity). 
Sequence Annotation
  
Keyword
 Cell junction; Cell membrane; Complete proteome; Gap junction; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
RMCCSFLRQL LARESQHSTP VGRFLLPVLV GFRLLILVSS GPGVFGNDEN EFMCHLGQPG 60
CKTICYDVFR PLSPLRFWAF QVILMAVPSA IYVAFTLYHV IGYWEVPGRN KEQEAQICKG 120
GRCKDVSGAM SLKLLWAYVA HLGVRLVLEG AALGVQYHLY GFKMPSTFIC REDPCIGSTT 180
CFQSHPSEKT ILLNTMFGIS GACLLFIFLE LVLLGLGRVW KTYRHKLPLF KNLSTSERSV 240
RHKDTTDDLS VVETKEPF 258 
Gene Ontology
 GO:0005922; C:connexon complex; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043209; C:myelin sheath; IEA:Compara.
 GO:0042552; P:myelination; IEA:Compara.
 GO:0007605; P:sensory perception of sound; IEA:Compara. 
Interpro
 IPR000500; Connexin.
 IPR019570; Connexin_CCC.
 IPR017990; Connexin_CS.
 IPR013092; Connexin_N. 
Pfam
 PF00029; Connexin
 PF10582; Connexin_CCC 
SMART
 SM01089; Connexin_CCC 
PROSITE
 PS00407; CONNEXINS_1
 PS00408; CONNEXINS_2 
PRINTS
 PR00206; CONNEXIN.