UniProt Accession

 TMED7_HUMAN; Q9Y3B3; Q8NBU8; Q8WUU6; Q96K51 

Genbank Protein ID

 AF151867; AK027512; AK074962; AK075218; AC010226; BC019349 

Genbank Nucleotide ID

 AAD34104.1; BAB55166.1; BAC11318.1; BAC11479.1; AAH19349.1 

Protein Name

 Transmembrane emp24 domain-containing protein 7 

Protein Synonyms/Alias

 p24 family protein gamma-3; p24gamma3; p27 

Gene Name

 TMED7 

Gene Synonyms/Alias

 CGI-109 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
83	RLEDPDGKVLYKEMK	ubiquitination	[1]
87	PDGKVLYKEMKKQYD	ubiquitination	[1]
91	VLYKEMKKQYDSFTF	ubiquitination	[1]
215	LKSFFSDKRTTTTRV	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post- translational modifications. 

Sequence Annotation

 DOMAIN 46 128 GOLD.
 MOTIF 211 224 COPI vesicle coat-binding (Potential).
 MOTIF 211 212 COPII vesicle coat-binding (Potential).
 CARBOHYD 103 103 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Cytoplasmic vesicle; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Membrane; Protein transport; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 224 AA 

Protein Sequence

Gene Ontology

 GO:0030126; C:COPI vesicle coat; TAS:UniProtKB.
 GO:0030127; C:COPII vesicle coat; TAS:UniProtKB.
 GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
 GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR009038; GOLD.
 IPR015718; P24-related. 

Pfam

 PF01105; EMP24_GP25L 

SMART

  

PROSITE

 PS50866; GOLD 

PRINTS